Heart

Dylan V. Miller, Hannah Krigman, Charles Canter

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Abstract

The aim of this chapter is to present the pathology of cardiac allograft rejection along with a brief historical background and summary of the clinical context and recent controversies. The intended audience is primarily pathologists, though it is also intended as a resource for heart failure/transplant investigators, clinicians, and surgeons seeking to better understand allograft biopsy interpretation. Different patterns of rejection are illustrated with emphasis on the most recent ISHLT working formulation classification schemes for cellular and antibody mediated rejection. An extensive discussion of immunopathology is also included. Nonrejection pathology encountered in transplant endomyocardial biopsies is addressed, including cardiac allograft vasculopathy. A brief section on the use of molecular pathology in rejection surveillance concludes the chapter.

Original languageEnglish (US)
Title of host publicationPathology of Solid Organ Transplantation
PublisherSpringer Berlin Heidelberg
Pages315-345
Number of pages31
ISBN (Print)9783540793427
DOIs
StatePublished - Dec 1 2011

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    Miller, D. V., Krigman, H., & Canter, C. (2011). Heart. In Pathology of Solid Organ Transplantation (pp. 315-345). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-540-79343-4_9