Detoxification of massive cyanide (CN) poisoning by inhalation of antidotes is recognized to be superior to intra venous (IV) or intra muscular (IM) treatment with regard to ease of administration, self-administration, and rapidity of onset. However, there are currently no effective, portable, high-throughput inhalers that can be produced in large quantities and distributed for such purpose. A hand-held inhaler has been realized using silicon-based ultrasonic nozzle to produce high-throughput of monodisperse cobinamide antidote solution for detoxification of CN poisoning in a rabbit model.
|Original language||English (US)|
|Title of host publication||2012 IEEE International Ultrasonics Symposium, IUS 2012|
|Number of pages||3|
|State||Published - 2012|
|Event||2012 IEEE International Ultrasonics Symposium, IUS 2012 - Dresden, Germany|
Duration: Oct 7 2012 → Oct 10 2012
|Name||IEEE International Ultrasonics Symposium, IUS|
|Other||2012 IEEE International Ultrasonics Symposium, IUS 2012|
|Period||10/7/12 → 10/10/12|
Copyright 2013 Elsevier B.V., All rights reserved.
- Fourier-horn ultrasonic nozzles
- cobinamide antidote
- cyanide poisoning and detoxification
- monodisperse aerosol inhaler