Keyphrases
Transcriptome
100%
H3K27M
100%
K27M mutation
100%
Chromatin Accessibility
100%
Diffuse Midline Glioma
100%
H3K27me3
100%
Polycomb Repressive Complex 2 (PRC2)
53%
EZH1
23%
Gliomagenesis
15%
Tumorigenesis
15%
Biological Pathways
15%
Pathway Activity
15%
Gene Expression
7%
Tumor
7%
Xenograft
7%
Lysine
7%
Gene Regulation
7%
Novel Mechanism
7%
Epigenomics
7%
Histone
7%
Isogenic
7%
Gene Cluster
7%
Epigenetic Effects
7%
Independent Functions
7%
Tumor Development
7%
Global Reduction
7%
RNA Sequencing (RNA-seq)
7%
Gene Activation
7%
Glioma Patients
7%
Enhancer of Zeste Homolog 2 (EZH2)
7%
Methyltransferase Activity
7%
Oncogenic Drivers
7%
Hox Genes
7%
Gene Induction
7%
Trimethylation
7%
H3.3
7%
Codeletion
7%
H3K27 Acetylation
7%
Patient-derived Cell Line
7%
ATAC-seq
7%
Global Redistribution
7%
CRISPR-Cas9 Editing
7%
Upregulated Genes
7%
Knockout Cells
7%
Gene Deregulation
7%
Biochemistry, Genetics and Molecular Biology
Polycomb Repressive Complex 2
100%
H3F3A
100%
Transcriptome
100%
Chromatin Accessibility
100%
EZH1
42%
Carcinogenesis
42%
Methylation
28%
Wild Type
28%
Epigenetics
14%
CRISPR/Cas9
14%
RNA Sequencing
14%
EZH2
14%
ATAC-Seq
14%
Gene Expression
14%
Gene Control
14%
Gene Activation
14%
Gene Induction
14%
Gene Cluster
14%
Methyltransferase
14%
Histone
14%
Lysine
14%