Gyrification differences in children and adolescents with velocardiofacial syndrome and attention-deficit/hyperactivity disorder: A pilot study

Sabine E. Mous, Canan Karatekin, Chiu Yen Kao, Irving I. Gottesman, Danielle Posthuma, Tonya White

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

We used magnetic resonance imaging to investigate brain gyrification patterns between 19 children with attention-deficit/hyperactivity disorder (ADHD), 9 children with velocardiofacial syndrome (VCFS), and 23 control children. We found that VCFS is associated with widespread decreases in gyrification. In ADHD, we found minor differences from control children. No evidence was found for common gyrification patterns between VCFS and ADHD children.

Original languageEnglish (US)
Pages (from-to)169-171
Number of pages3
JournalPsychiatry Research - Neuroimaging
Volume221
Issue number2
DOIs
StatePublished - Feb 28 2014

Bibliographical note

Funding Information:
This work was supported by the National Association for Research in Schizophrenia and Affective Disorders (NARSAD) , currently named the Brain and Behavior Research Foundation via the generous contribution from the Blowitz-Ridgeway Foundation , NIMH K08 MH068540 , the Center for Neurobehavioral Development at the University of Minnesota , NWO ZonMw TOP project number 91211021 , and Brain & Cognition (Hersenen & Cognitie) project number 433-09-228 . We also thank Marcus Schmidt and Angela Guimaraes for their assistance with the study. None of the authors reported any biomedical financial interests or potential conflicts of interest.

Keywords

  • Attention-deficit/hyperactivity disorder (ADHD)
  • Brain gyrification
  • Velocardiofacial syndrome (VCFS)

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