Guiding Ethical Principles in Engineering Biology Research

Rebecca Mackelprang; Emily R. Aurand; Roel A.L. Bovenberg; Kathryn R. Brink; R. Alta Charo; Jason A. Delborne; James Diggans; Andrew D. Ellington; Jeffrey L."clem" Fortman; Farren J. Isaacs; June I. Medford; Richard M. Murray; Vincent Noireaux; Megan J. Palmer; Laurie Zoloth; Douglas C. Friedman

doi:10.1021/acssynbio.1c00129

Guiding Ethical Principles in Engineering Biology Research

Rebecca Mackelprang, Emily R. Aurand, Roel A.L. Bovenberg, Kathryn R. Brink, R. Alta Charo, Jason A. Delborne, James Diggans, Andrew D. Ellington, Jeffrey L."clem" Fortman, Farren J. Isaacs, June I. Medford, Richard M. Murray, Vincent Noireaux, Megan J. Palmer, Laurie Zoloth, Douglas C. Friedman

Physics and Astronomy (Twin Cities)

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Engineering biology is being applied toward solving or mitigating some of the greatest challenges facing society. As with many other rapidly advancing technologies, the development of these powerful tools must be considered in the context of ethical uses for personal, societal, and/or environmental advancement. Researchers have a responsibility to consider the diverse outcomes that may result from the knowledge and innovation they contribute to the field. Together, we developed a Statement of Ethics in Engineering Biology Research to guide researchers as they incorporate the consideration of long-term ethical implications of their work into every phase of the research lifecycle. Herein, we present and contextualize this Statement of Ethics and its six guiding principles. Our goal is to facilitate ongoing reflection and collaboration among technical researchers, social scientists, policy makers, and other stakeholders to support best outcomes in engineering biology innovation and development.

Original language	English (US)
Pages (from-to)	907-910
Number of pages	4
Journal	ACS Synthetic Biology
Volume	10
Issue number	5
DOIs	https://doi.org/10.1021/acssynbio.1c00129
State	Published - May 21 2021

Bibliographical note

Funding Information:
R.M., J.L.F., E.R.A., and D.C.F. were supported by the Department of Homeland Security under Award No. 19STFRG00011-01-00. E.R.A. and D.C.F. were supported by the National Science Foundation (NSF) under Award No. 1818248. K.R.B. was supported by the Office of Naval Research N00014-18-1-2611, NSF MCB-1553317, Rice University Nettie S. Autrey Fellowship (2020–2021). A.D.E. was supported by The Welch Foundation F-1654. F.J.I. was supported by NSF awards MCB-1714860, EF-1935120, and IOS-1923321. V.N. was supported by NSF awards MCB-1613677 and MCB-2017932. The views and conclusions contained in this document are those of the authors and should not be interpreted as necessarily representing the official policies, either expressed or implied, of the U.S. Department of Homeland Security.

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Mackelprang, R., Aurand, E. R., Bovenberg, R. A. L., Brink, K. R., Charo, R. A., Delborne, J. A., Diggans, J., Ellington, A. D., Fortman, J. L., Isaacs, F. J., Medford, J. I., Murray, R. M., Noireaux, V., Palmer, M. J., Zoloth, L., & Friedman, D. C. (2021). Guiding Ethical Principles in Engineering Biology Research. ACS Synthetic Biology, 10(5), 907-910. https://doi.org/10.1021/acssynbio.1c00129

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abstract = "Engineering biology is being applied toward solving or mitigating some of the greatest challenges facing society. As with many other rapidly advancing technologies, the development of these powerful tools must be considered in the context of ethical uses for personal, societal, and/or environmental advancement. Researchers have a responsibility to consider the diverse outcomes that may result from the knowledge and innovation they contribute to the field. Together, we developed a Statement of Ethics in Engineering Biology Research to guide researchers as they incorporate the consideration of long-term ethical implications of their work into every phase of the research lifecycle. Herein, we present and contextualize this Statement of Ethics and its six guiding principles. Our goal is to facilitate ongoing reflection and collaboration among technical researchers, social scientists, policy makers, and other stakeholders to support best outcomes in engineering biology innovation and development.",

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note = "Funding Information: R.M., J.L.F., E.R.A., and D.C.F. were supported by the Department of Homeland Security under Award No. 19STFRG00011-01-00. E.R.A. and D.C.F. were supported by the National Science Foundation (NSF) under Award No. 1818248. K.R.B. was supported by the Office of Naval Research N00014-18-1-2611, NSF MCB-1553317, Rice University Nettie S. Autrey Fellowship (2020–2021). A.D.E. was supported by The Welch Foundation F-1654. F.J.I. was supported by NSF awards MCB-1714860, EF-1935120, and IOS-1923321. V.N. was supported by NSF awards MCB-1613677 and MCB-2017932. The views and conclusions contained in this document are those of the authors and should not be interpreted as necessarily representing the official policies, either expressed or implied, of the U.S. Department of Homeland Security. Publisher Copyright: {\textcopyright} ",

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AU - Mackelprang, Rebecca

AU - Aurand, Emily R.

AU - Bovenberg, Roel A.L.

AU - Brink, Kathryn R.

AU - Charo, R. Alta

AU - Delborne, Jason A.

AU - Diggans, James

AU - Ellington, Andrew D.

AU - Fortman, Jeffrey L."clem"

AU - Isaacs, Farren J.

AU - Medford, June I.

AU - Murray, Richard M.

AU - Noireaux, Vincent

AU - Palmer, Megan J.

AU - Zoloth, Laurie

AU - Friedman, Douglas C.

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Guiding Ethical Principles in Engineering Biology Research

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