TY - JOUR
T1 - Guidelines for the early management of adults with ischemic stroke
T2 - A guideline from the American heart association/American stroke association stroke council, clinical cardiology council, cardiovascular radiology and intervention council, and the atherosclerotic peripheral vascular disease and quality of care outcomes in research interdisciplinary working groups:
AU - Adams, Harold P.
AU - Del Zoppo, Gregory
AU - Alberts, Mark J.
AU - Bhatt, Deepak L.
AU - Brass, Lawrence
AU - Furlan, Anthony
AU - Grubb, Robert L.
AU - Higashida, Randall T.
AU - Jauch, Edward C.
AU - Kidwell, Chelsea
AU - Lyden, Patrick D.
AU - Morgenstern, Lewis B.
AU - Qureshi, Adnan I.
AU - Rosenwasser, Robert H.
AU - Scott, Phillip A.
AU - Wijdicks, Eelco F.M.
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2007/5
Y1 - 2007/5
N2 - PURPOSE - Our goal is to provide an overview of the current evidence about components of the evaluation and treatment of adults with acute ischemic stroke. The intended audience is physicians and other emergency healthcare providers who treat patients within the first 48 hours after stroke. In addition, information for healthcare policy makers is included. METHODS - Members of the panel were appointed by the American Heart Association Stroke Council's Scientific Statement Oversight Committee and represented different areas of expertise. The panel reviewed the relevant literature with an emphasis on reports published since 2003 and used the American Heart Association Stroke Council's Levels of Evidence grading algorithm to rate the evidence and to make recommendations. After approval of the statement by the panel, it underwent peer review and approval by the American Heart Association Science Advisory and Coordinating Committee. It is intended that this guideline be fully updated in 3 years. RESULTS - Management of patients with acute ischemic stroke remains multifaceted and includes several aspects of care that have not been tested in clinical trials. This statement includes recommendations for management from the first contact by emergency medical services personnel through initial admission to the hospital. Intravenous administration of recombinant tissue plasminogen activator remains the most beneficial proven intervention for emergency treatment of stroke. Several interventions, including intra-arterial administration of thrombolytic agents and mechanical interventions, show promise. Because many of the recommendations are based on limited data, additional research on treatment of acute ischemic stroke is needed.
AB - PURPOSE - Our goal is to provide an overview of the current evidence about components of the evaluation and treatment of adults with acute ischemic stroke. The intended audience is physicians and other emergency healthcare providers who treat patients within the first 48 hours after stroke. In addition, information for healthcare policy makers is included. METHODS - Members of the panel were appointed by the American Heart Association Stroke Council's Scientific Statement Oversight Committee and represented different areas of expertise. The panel reviewed the relevant literature with an emphasis on reports published since 2003 and used the American Heart Association Stroke Council's Levels of Evidence grading algorithm to rate the evidence and to make recommendations. After approval of the statement by the panel, it underwent peer review and approval by the American Heart Association Science Advisory and Coordinating Committee. It is intended that this guideline be fully updated in 3 years. RESULTS - Management of patients with acute ischemic stroke remains multifaceted and includes several aspects of care that have not been tested in clinical trials. This statement includes recommendations for management from the first contact by emergency medical services personnel through initial admission to the hospital. Intravenous administration of recombinant tissue plasminogen activator remains the most beneficial proven intervention for emergency treatment of stroke. Several interventions, including intra-arterial administration of thrombolytic agents and mechanical interventions, show promise. Because many of the recommendations are based on limited data, additional research on treatment of acute ischemic stroke is needed.
KW - AHA Scientific Statements
KW - Acute cerebral infarction
KW - Emergency medical services
KW - Stroke
KW - Tissue plasminogen activator
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U2 - 10.1161/STROKEAHA.107.181486
DO - 10.1161/STROKEAHA.107.181486
M3 - Review article
C2 - 17431204
AN - SCOPUS:34247844511
SN - 0039-2499
VL - 38
SP - 1655
EP - 1711
JO - Stroke
JF - Stroke
IS - 5
ER -