Guideline for the prevention, diagnosis and management of cryptococcal meningitis among HIV-infected persons: 2013 update

N. P. Govender, G. Meintjes, T. Bicanic, H. Dawood, T. S. Harrison, J. N. Jarvis, A. S. Karstaedt, G. Maartens, K. M. McCarthy, H. Rabie, E. Variava, W. D.F. Venter, D. R. Boulware, T. Chiller, D. B. Meya, J. Scriven

Research output: Contribution to journalArticlepeer-review

69 Scopus citations

Abstract

Six years after the first Society guidelines were published, cryptococcal meningitis (CM) remains an important cause of morbidity and mortality among HIV-infected adults in South Africa. Several important developments have spurred the publication of updated guidelines to manage this common fungal opportunistic infection. Recommendations described here include: (1) screening and pre-emptive treatment; (2) laboratory diagnosis and monitoring; (3) management of a first episode of CM; (4) amphotericin B deoxycholate toxicity prevention, monitoring and management; (5) timing of antiretroviral therapy among patients with CM; (6) management of raised intracranial pressure; (7) management of relapse episodes of CM.

Original languageEnglish (US)
Pages (from-to)76-86
Number of pages11
JournalSouthern African Journal of HIV Medicine
Volume14
Issue number2
DOIs
StatePublished - Jun 2013

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