Guanosine 5' diphosphate, 3' diphosphate: Assignment of structure by 13C nuclear magnetic resonance spectroscopy

L. Que; G. R. Willie; M. Cashel; J. W. Bodley; G. R. Gray

doi:10.1073/pnas.70.9.2563

Guanosine 5' diphosphate, 3' diphosphate: Assignment of structure by ¹³C nuclear magnetic resonance spectroscopy

L. Que, G. R. Willie, M. Cashel, J. W. Bodley, G. R. Gray

Chemistry (Twin Cities)

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Guanosine tetraphosphate, recently discovered to mediate the regulatory relationship between protein synthesis and RNA accumulation in various bacteria, has been synthesized in vitro in large quantities and analyzed by natural abundance ¹³C nuclear magnetic resonance spectroscopy in order to confirm its structure and establish the positions of phosphate attachment. These studies have established its structure as guanosine 5' diphosphate, 3' diphosphate.

Original language	English (US)
Pages (from-to)	2563-2566
Number of pages	4
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	70
Issue number	9
DOIs	https://doi.org/10.1073/pnas.70.9.2563
State	Published - 1973

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10.1073/pnas.70.9.2563

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abstract = "Guanosine tetraphosphate, recently discovered to mediate the regulatory relationship between protein synthesis and RNA accumulation in various bacteria, has been synthesized in vitro in large quantities and analyzed by natural abundance 13C nuclear magnetic resonance spectroscopy in order to confirm its structure and establish the positions of phosphate attachment. These studies have established its structure as guanosine 5' diphosphate, 3' diphosphate.",

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year = "1973",

doi = "10.1073/pnas.70.9.2563",

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T1 - Guanosine 5' diphosphate, 3' diphosphate

T2 - Assignment of structure by 13C nuclear magnetic resonance spectroscopy

AU - Que, L.

AU - Willie, G. R.

AU - Cashel, M.

AU - Bodley, J. W.

AU - Gray, G. R.

PY - 1973

Y1 - 1973

N2 - Guanosine tetraphosphate, recently discovered to mediate the regulatory relationship between protein synthesis and RNA accumulation in various bacteria, has been synthesized in vitro in large quantities and analyzed by natural abundance 13C nuclear magnetic resonance spectroscopy in order to confirm its structure and establish the positions of phosphate attachment. These studies have established its structure as guanosine 5' diphosphate, 3' diphosphate.

AB - Guanosine tetraphosphate, recently discovered to mediate the regulatory relationship between protein synthesis and RNA accumulation in various bacteria, has been synthesized in vitro in large quantities and analyzed by natural abundance 13C nuclear magnetic resonance spectroscopy in order to confirm its structure and establish the positions of phosphate attachment. These studies have established its structure as guanosine 5' diphosphate, 3' diphosphate.

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Guanosine 5' diphosphate, 3' diphosphate: Assignment of structure by ¹³C nuclear magnetic resonance spectroscopy

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