Growth of hybridoma cells under different agitation conditions

Timothy C. Dodge, Wei Shou Hu

Research output: Contribution to journalArticlepeer-review

43 Scopus citations


The effect of mechanical agitation on hybridoma cell growth was examined in laboratory scale vessels. At an agitation rate four times that required to keep the cells in suspension, both growth rate and growth extent were reduced. However, using the minimum agitation rate required to suspend cells, no adverse effect on cell growth was observed even with a turbine agitator.

Original languageEnglish (US)
Pages (from-to)683-686
Number of pages4
JournalBiotechnology Letters
Issue number10
StatePublished - Oct 1 1986


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