Growth of bioactive surfaces on titanium and its alloys for orthopaedic and dental implants

F. J. Gil; A. Padrós; J. M. Manero; C. Aparicio; M. Nilsson; J. A. Planell

doi:10.1016/S0928-4931(01)00389-7

Growth of bioactive surfaces on titanium and its alloys for orthopaedic and dental implants

F. J. Gil, A. Padrós, J. M. Manero, C. Aparicio, M. Nilsson, J. A. Planell

Restorative Sciences

Research output: Contribution to journal › Article › peer-review

73 Scopus citations

Abstract

A simple chemical method was established for inducing bioactivity of titanium and its alloys. Recently, T. Kokubo demonstrated that an in vitro chemical-deposited bone-like apatite on Ti with bone-bonding ability could be induced. Following treatment, a dense bone-like apatite layer is formed on the surface of the titanium in simulated body fluid (SBF). Observation of the samples in wet state by means of the environmental scanning electron microscope (ESEM) enabled us to observe the calcium phosphate deposition process in situ over a number of days. One of the most important features of the study is that it was carried out on a single, unchanged titanium sample and the process was not at any stage interrupted. Moreover, it was demonstrated that human osteoblast adhesion and differentiation behaviour are better in bioactive titanium than in the titanium without the chemical treatment.

Original language	English (US)
Pages (from-to)	53-60
Number of pages	8
Journal	Materials Science and Engineering C
Volume	22
Issue number	1
DOIs	https://doi.org/10.1016/S0928-4931(01)00389-7
State	Published - Oct 1 2002

Bibliographical note

Funding Information:
This work was supported by CICYT project MAT-98-0415 and by Klockner Impants. The authors are specially grateful to Mercedes Roldán Chesa.

Keywords

Apatite
Bioactivity
Biomaterials

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title = "Growth of bioactive surfaces on titanium and its alloys for orthopaedic and dental implants",

abstract = "A simple chemical method was established for inducing bioactivity of titanium and its alloys. Recently, T. Kokubo demonstrated that an in vitro chemical-deposited bone-like apatite on Ti with bone-bonding ability could be induced. Following treatment, a dense bone-like apatite layer is formed on the surface of the titanium in simulated body fluid (SBF). Observation of the samples in wet state by means of the environmental scanning electron microscope (ESEM) enabled us to observe the calcium phosphate deposition process in situ over a number of days. One of the most important features of the study is that it was carried out on a single, unchanged titanium sample and the process was not at any stage interrupted. Moreover, it was demonstrated that human osteoblast adhesion and differentiation behaviour are better in bioactive titanium than in the titanium without the chemical treatment.",

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note = "Funding Information: This work was supported by CICYT project MAT-98-0415 and by Klockner Impants. The authors are specially grateful to Mercedes Rold{\'a}n Chesa.",

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AU - Padrós, A.

AU - Manero, J. M.

AU - Aparicio, C.

AU - Nilsson, M.

AU - Planell, J. A.

N1 - Funding Information: This work was supported by CICYT project MAT-98-0415 and by Klockner Impants. The authors are specially grateful to Mercedes Roldán Chesa.

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N2 - A simple chemical method was established for inducing bioactivity of titanium and its alloys. Recently, T. Kokubo demonstrated that an in vitro chemical-deposited bone-like apatite on Ti with bone-bonding ability could be induced. Following treatment, a dense bone-like apatite layer is formed on the surface of the titanium in simulated body fluid (SBF). Observation of the samples in wet state by means of the environmental scanning electron microscope (ESEM) enabled us to observe the calcium phosphate deposition process in situ over a number of days. One of the most important features of the study is that it was carried out on a single, unchanged titanium sample and the process was not at any stage interrupted. Moreover, it was demonstrated that human osteoblast adhesion and differentiation behaviour are better in bioactive titanium than in the titanium without the chemical treatment.

AB - A simple chemical method was established for inducing bioactivity of titanium and its alloys. Recently, T. Kokubo demonstrated that an in vitro chemical-deposited bone-like apatite on Ti with bone-bonding ability could be induced. Following treatment, a dense bone-like apatite layer is formed on the surface of the titanium in simulated body fluid (SBF). Observation of the samples in wet state by means of the environmental scanning electron microscope (ESEM) enabled us to observe the calcium phosphate deposition process in situ over a number of days. One of the most important features of the study is that it was carried out on a single, unchanged titanium sample and the process was not at any stage interrupted. Moreover, it was demonstrated that human osteoblast adhesion and differentiation behaviour are better in bioactive titanium than in the titanium without the chemical treatment.

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Growth of bioactive surfaces on titanium and its alloys for orthopaedic and dental implants

Abstract

Bibliographical note

Keywords

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