Growth inhibition and induction of apoptosis in MCF-7 breast cancer cells by a new series of substituted-1,3,4-oxadiazole derivatives

Keyphrases

• Apoptosis Induction 100%
• Breast Cancer Cells 100%
• Growth Inhibition 100%
• Apoptosis Inhibition 100%
• MCF-7 100%
• MCF-7 Cells 100%
• Growth Induction 100%
• 1,3,4-Oxadiazole Derivatives 100%
• New Series 100%
• Induced Apoptosis 66%
• Apoptosis 66%
• Pharmacological Activities 66%
• Cell Viability 33%
• Biological Activity 33%
• B-cell Lymphoma 2 (Bcl-2) 33%
• Drug Substance 33%
• Antiproliferative Activity 33%
• Oncoprotein 33%
• Protein Level 33%
• Caspase-3 33%
• Phase Accumulation 33%
• DNA Fragmentation 33%
• Chromatin Condensation 33%
• DNase 33%
• Activity Inhibition 33%
• Bax Protein 33%
• Event Sequences 33%
• G(0) 33%
• 1,3,4-oxadiazole 33%
• Anticancer Properties 33%
• Heterocyclic Compounds 33%
• Synthetic Compounds 33%
• Dependent Sequence 33%
• Oxadiazole Derivatives 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Breast Cancer 100%
• Oxadiazole Derivative 100%
• 1,3,4 Oxadiazole Derivative 100%
• Drug Action 100%
• Biological Activity 50%
• Cell Viability 50%
• Malignant Neoplasm 50%
• Protein Bax 50%
• Oncoprotein 50%
• Heterocyclic Compound 50%
• Disease 50%
• Caspase 3 50%
• Deoxyribonuclease 50%