Growth failure in international adoptees

Bradley S Miller, Dana E Johnson, Judith Eckerle Kang, Anna Petryk

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Psychosocial growth failure, represented by significant suppression of height, weight, and head circumference at the time of adoption, is highly prevalent in children who are adopted internationally. The effects of institutional deprivation are more profound in children with a higher baseline risk of growth impairment (low birth weight or high risk for prenatal alcohol exposure). Nutritional insufficiency and social deprivation both contribute to the etiology of psychosocial growth failure within institutional care settings. Their relative importance and the consequent clinical presentations relate to the age of the child, with inadequate nutrition contributing more in infancy and early childhood and depression of hypothalamic-pituitary-end organ function, particularly the GH-IGF-1 axis, becoming more important as children age. Both malnutrition and deprivation are associated with suppression of the GH-IGF-1 axis. Children who have experienced institutional care are at an increased risk of medical, developmental, and behavioral problems. Therefore, international adoptees should be carefully evaluated at the time of arrival into their new home country and followed closely as they make the transition to their new home environment. They should be monitored for adequate auxologic and neurocognitive catch-up over time. Children not making appropriate progress should be referred for specialty evaluation. Growth failure at the time of adoption, along with catch-up growth in height and weight, is a risk factor for early and/or more rapid progression through puberty in girls leading to a compromise in final height. There is also reason for concern that children with psychosocial growth failure may be at increased risk of developing metabolic syndrome. Even if growth recovers, persistent abnormalities of the endocrine system or the presence of micronutrient deficiencies during critical periods of development could potentially influence or be responsible for the cognitive, behavioral, and emotional sequelae of early childhood deprivation. Infants of low birth weight are particularly vulnerable to the effects of nutritional and social deprivation. This significant impact of psychosocial growth failure on low birth weight infants extends beyond the plight of institutionalized children to the millions of impoverished children worldwide. Psychosocial deprivation within any caregiving environment during early life is as detrimental as malnutrition and must be viewed with as much concern as any severely debilitating childhood disease.

Original languageEnglish (US)
Title of host publicationHandbook of Growth and Growth Monitoring in Health and Disease
PublisherSpringer New York
Pages2003-2021
Number of pages19
ISBN (Electronic)9781441917959
ISBN (Print)9781441917942
DOIs
StatePublished - Jan 1 2012

Fingerprint

Growth
Low Birth Weight Infant
Insulin-Like Growth Factor I
Malnutrition
Psychosocial Deprivation
Institutionalized Child
Weights and Measures
Endocrine System
Micronutrients
Puberty
Head
Alcohols

Cite this

Miller, B. S., Johnson, D. E., Kang, J. E., & Petryk, A. (2012). Growth failure in international adoptees. In Handbook of Growth and Growth Monitoring in Health and Disease (pp. 2003-2021). Springer New York. https://doi.org/10.1007/978-1-4419-1795-9_122

Growth failure in international adoptees. / Miller, Bradley S; Johnson, Dana E; Kang, Judith Eckerle; Petryk, Anna.

Handbook of Growth and Growth Monitoring in Health and Disease. Springer New York, 2012. p. 2003-2021.

Research output: Chapter in Book/Report/Conference proceedingChapter

Miller, BS, Johnson, DE, Kang, JE & Petryk, A 2012, Growth failure in international adoptees. in Handbook of Growth and Growth Monitoring in Health and Disease. Springer New York, pp. 2003-2021. https://doi.org/10.1007/978-1-4419-1795-9_122
Miller BS, Johnson DE, Kang JE, Petryk A. Growth failure in international adoptees. In Handbook of Growth and Growth Monitoring in Health and Disease. Springer New York. 2012. p. 2003-2021 https://doi.org/10.1007/978-1-4419-1795-9_122
Miller, Bradley S ; Johnson, Dana E ; Kang, Judith Eckerle ; Petryk, Anna. / Growth failure in international adoptees. Handbook of Growth and Growth Monitoring in Health and Disease. Springer New York, 2012. pp. 2003-2021
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