Granulosa cell tumor in an ovariohysterectomized dog.

G. E. Pluhar, M. A. Memon, L. G. Wheaton

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


A granulosa cell tumor was found in a dog with clinical signs of persistent estrus that began 6 years after ovariohysterectomy had been performed. The tumor was diagnosed by use of ultrasonography, provocative testing with human chorionic gonadotropin, and exploratory laparotomy. Hyperestrogenism from functional tumor cells caused bone marrow suppression and endocrine alopecia. Successful treatment included tumor removal, blood transfusions, and antibiotic administration.

Original languageEnglish (US)
Pages (from-to)1063-1065
Number of pages3
JournalJournal of the American Veterinary Medical Association
Issue number8
StatePublished - Oct 15 1995


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