Granulocytic ehrlichiosis in tick-immune guinea pigs.

S. Das, K. Deponte, N. L. Marcantonio, J. W. Ijdo, E. Hodzic, P. Katavolos, S. W. Barthold, S. R. Telford, F. S. Kantor, E. Fikrig

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


We investigated whether Ixodes scapularis-mediated host immunity interrupts transmission of the agent of human granulocytic ehrlichiosis (aoHGE) to guinea pigs. Ticks infected with aoHGE readily transmitted aoHGE to tick-immune guinea pigs, despite incomplete tick engorgement and host attachment. Although tick immunity can prevent Lyme borreliosis, protection is not afforded against granulocytic ehrlichiosis.

Original languageEnglish (US)
Pages (from-to)1803-1805
Number of pages3
JournalInfection and immunity
Issue number4
StatePublished - Apr 1998
Externally publishedYes


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