Gram-Scale Synthesis of 2,5-Difluoro-7,7,8,8-tetracyanoquinodimethane (F2-TCNQ)

En Chih Liu, Joseph J. Topczewski

Research output: Contribution to journalArticlepeer-review


The molecule 2,5-difluoro-7,7,8,8-tetracyanoquinodimethane (F2-TCNQ) is an organic semiconductor with many promising properties, including high charge mobility (μ). However, an efficient gram-scale synthesis of F2-TCNQ has not been fully documented. Herein, we report a synthesis of F2-TCNQ via a three-step sequence that affords F2-TCNQ in 58% cumulative yield. This synthesis was used to prepare more than 1 g of F2-TCNQ.

Original languageEnglish (US)
Pages (from-to)4560-4564
Number of pages5
JournalJournal of Organic Chemistry
Issue number6
StatePublished - Mar 20 2020

Bibliographical note

Funding Information:
We thank Prof. Aaron Massari (UMN) for suggesting this target. This work was supported by the University of Minnesota.

Publisher Copyright:
Copyright © 2020 American Chemical Society.


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