Gram-negative bacterial sepsis and the sepsis syndrome

V. Lazaron, R. A. Barke

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Gram-negative sepsis syndrome is an increasingly common complication in medical and surgical patients. The molecular and cellular mechanisms underlying this dreaded complication are yielding to investigation. These studies have led to a multiplicity of targets for novel therapies. Despite highly promising results in many animal studies, clinical studies have been disappointing.

Original languageEnglish (US)
Pages (from-to)687-699
Number of pages13
JournalUrologic Clinics of North America
Issue number4
StatePublished - 1999
Externally publishedYes

Bibliographical note

Funding Information:
This work was supported in part by grants from North Trauma Institute, North Memorial Health Care, and the Department of Defense.


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