Good outcome in prune-belly syndrome despite associated severe anomalies

Israel Zelikovic, Shermine Dabbagh, Aaron L. Friedman, David T. Uehling, Russell W. Chesney

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

A boy aged 4.5 years with prune-belly syndrome (PBS) and associated urethral stenosis, oligohydramnios, imperforate anus and vesicosigmoid fustula is described. In contrast to the anticipated poor prognosis, vesicostomy and divided transverse colostomy performed after birth followed by prophylaxis of infection and bicarbonate supplementation have resulted in a good outcome. The vesicosigmoid fistula might have served in utero as a "natural diversion" protecting from pressure-induced renal damage. It is suggested that the main determinant of prognosis in PBS is the presence and degree of kidney dysplasia at birth as reflected by the neonatal renal function after performance of an indicated urinary diversion procedure rather than the presence of severe associated anomalies.

Original languageEnglish (US)
Pages (from-to)512-514
Number of pages3
JournalPediatric Nephrology
Volume2
Issue number4
DOIs
StatePublished - Dec 1 1988

Keywords

  • Imperforate anus
  • Oligohydramnios
  • Prune-belly syndrome
  • Urethral stenosis

Fingerprint Dive into the research topics of 'Good outcome in prune-belly syndrome despite associated severe anomalies'. Together they form a unique fingerprint.

Cite this