Abstract
A gold nanotip array platform with a combination of ultrasensitive electrochemical sensing and spectroscopic monitoring capability is reported. Adenosine triphosphate is detected down to 1 pM according to the impedance changes in response to aptamer-specific binding. Furthermore, the local molecular information can be monitored at the individual plasmonic nanotips, and hence provide the capability for a better understanding of complex biological processes.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2260-2265 |
| Number of pages | 6 |
| Journal | Small |
| Volume | 9 |
| Issue number | 13 |
| DOIs | |
| State | Published - Jul 8 2013 |
Keywords
- adenosine triphosphate
- nanotip arrays
- raman scattering
- redox electrochemistry
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