Glycoprotein B genotyping of cytomegalovirus strains isolated in a pediatric population

To better characterize cytomegalovirus (CMV) isolates in a pediatric population, we performed glycoprotein B genotyping of isolates from CMV culture-positive patients during a 3-year period at Children's Hospital Medical Center, Cincinnati, Ohio. The most common sources for CMV isolation were respiratory and urine cultures. Among 61 isolates glycoprotein B genotype distribution was: genotype 1, 32%; genotype 2, 24%, genotype 3, 32%; and genotype 4, 10%. Among viremic isolates there was a trend favoring type 1 genotype (P = 0.057).