Glucose-Neopentyl Glycol (GNG) amphiphiles for membrane protein study

Pil Seok Chae; Rohini R. Rana; Kamil Gotfryd; Søren G.F. Rasmussen; Andrew C. Kruse; Kyung Ho Cho; Stefano Capaldi; Emil Carlsson; Brian Kobilka; Claus J. Loland; Ulrik Gether; Surajit Banerjee; Bernadette Byrne; John K. Lee; Samuel H. Gellman

doi:10.1039/c2cc36844g

Glucose-Neopentyl Glycol (GNG) amphiphiles for membrane protein study

Pil Seok Chae, Rohini R. Rana, Kamil Gotfryd, Søren G.F. Rasmussen, Andrew C. Kruse, Kyung Ho Cho, Stefano Capaldi, Emil Carlsson, Brian Kobilka, Claus J. Loland, Ulrik Gether, Surajit Banerjee, Bernadette Byrne, John K. Lee, Samuel H. Gellman

Biochemistry, Molecular Biology, and Biophysics (TMED)

Research output: Contribution to journal › Article › peer-review

82 Scopus citations

Abstract

The development of a new class of surfactants for membrane protein manipulation, “GNG amphiphiles”, is reported. These amphiphiles display promising behavior for membrane proteins, as demonstrated recently by the high resolution structure of a sodium-pumping pyrophosphatase reported by Kellosalo et al. (Science, 2012, 337, 473).

Original language	English (US)
Pages (from-to)	2287-2289
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	23
DOIs	https://doi.org/10.1039/c2cc36844g
State	Published - Feb 21 2013

Publisher link

10.1039/c2cc36844g

Find It

Find It at U of M Libraries

Cite this

@article{d8fe4f0e404748a7b0fb04b3dafba511,

title = "Glucose-Neopentyl Glycol (GNG) amphiphiles for membrane protein study",

abstract = "The development of a new class of surfactants for membrane protein manipulation, “GNG amphiphiles”, is reported. These amphiphiles display promising behavior for membrane proteins, as demonstrated recently by the high resolution structure of a sodium-pumping pyrophosphatase reported by Kellosalo et al. (Science, 2012, 337, 473).",

author = "Chae, \{Pil Seok\} and Rana, \{Rohini R.\} and Kamil Gotfryd and Rasmussen, \{S{\o}ren G.F.\} and Kruse, \{Andrew C.\} and Cho, \{Kyung Ho\} and Stefano Capaldi and Emil Carlsson and Brian Kobilka and Loland, \{Claus J.\} and Ulrik Gether and Surajit Banerjee and Bernadette Byrne and Lee, \{John K.\} and Gellman, \{Samuel H.\}",

year = "2013",

month = feb,

day = "21",

doi = "10.1039/c2cc36844g",

language = "English (US)",

volume = "49",

pages = "2287--2289",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "23",

}

TY - JOUR

T1 - Glucose-Neopentyl Glycol (GNG) amphiphiles for membrane protein study

AU - Chae, Pil Seok

AU - Rana, Rohini R.

AU - Gotfryd, Kamil

AU - Rasmussen, Søren G.F.

AU - Kruse, Andrew C.

AU - Cho, Kyung Ho

AU - Capaldi, Stefano

AU - Carlsson, Emil

AU - Kobilka, Brian

AU - Loland, Claus J.

AU - Gether, Ulrik

AU - Banerjee, Surajit

AU - Byrne, Bernadette

AU - Lee, John K.

AU - Gellman, Samuel H.

PY - 2013/2/21

Y1 - 2013/2/21

N2 - The development of a new class of surfactants for membrane protein manipulation, “GNG amphiphiles”, is reported. These amphiphiles display promising behavior for membrane proteins, as demonstrated recently by the high resolution structure of a sodium-pumping pyrophosphatase reported by Kellosalo et al. (Science, 2012, 337, 473).

AB - The development of a new class of surfactants for membrane protein manipulation, “GNG amphiphiles”, is reported. These amphiphiles display promising behavior for membrane proteins, as demonstrated recently by the high resolution structure of a sodium-pumping pyrophosphatase reported by Kellosalo et al. (Science, 2012, 337, 473).

UR - https://www.scopus.com/pages/publications/84874820949

UR - https://www.scopus.com/inward/citedby.url?scp=84874820949&partnerID=8YFLogxK

U2 - 10.1039/c2cc36844g

DO - 10.1039/c2cc36844g

M3 - Article

C2 - 23165475

AN - SCOPUS:84874820949

SN - 1359-7345

VL - 49

SP - 2287

EP - 2289

JO - Chemical Communications

JF - Chemical Communications

IS - 23

ER -

Glucose-Neopentyl Glycol (GNG) amphiphiles for membrane protein study

Abstract

Publisher link

Find It

Other files and links

Fingerprint

Cite this