Glucose biosensors based on layer-by-layer nano self-assembled ion-sensitive field-effect transistors

Yi Liu, Tianhong Cui

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

This paper demonstrates the fabrication and characterization of two types of glucose biosensors based on layer-by-layer self-assembled ion-sensitive field-effect transistors (ISFET). One glucose biosensor uses the self-assembled indium oxide (In2O3) nanoparticle thin film as the channel, while the other employs the self-assembled semiconducting polymer polyaniline (PANI) thin film as the channel. The self-assembled silicon dioxide (SiO2) nanoparticle thin film serves as the gate dielectric for both types of ISFETs. For the In2O3 ISFET, the field-effect mobility is 38.66 cm2/Vs, and the sensitivity to glucose is 2.125 μA/mM. For the PANI ISFET, the mobility is 14.31 cm2 /Vs, and the sensitivity to glucose is 0.738 μA/mM. The results demonstrate that nanoparticles and polymers are very promising materials for the applications to low-cost biosensors.

Original languageEnglish (US)
Pages (from-to)241-245
Number of pages5
JournalSensor Letters
Volume4
Issue number3
DOIs
StatePublished - Sep 1 2006

Keywords

  • Biosensor
  • ISFET
  • Layer-by-layer nano self-assembly
  • Nanoparticle
  • Polymer

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