Glomus jugulare tumors: Effects of radiotherapy

Gershon J. Spector, John Compagno, Carlos A. Perez, Robert H. Maisel, Joseph H. Ogura

Research output: Contribution to journalArticlepeer-review

77 Scopus citations

Abstract

Twenty glomus jugulare tumors which received x‐ray therapy are analyzed. Postirradiation angiography showed persistent tumor vessels and abnormal channels in eight patients. Histologic study of five postirradiation specimens showed that tumor cells persisted after treatment in a significant proportion of the patients. Vascular response was nonuniform and consisted of endothelial hyperplasia and subendothelial hyalinization. Radiotherapy is not always effective in the permanent eradication of the tumor when used as the only modality of treatment in patients with large glomus jugulare tumors. Because of the frequent recurrence after irradiation or surgical resection, a combination of both modalities offers the patient the best probability of cure.

Original languageEnglish (US)
Pages (from-to)1316-1321
Number of pages6
JournalCancer
Volume35
Issue number5
DOIs
StatePublished - May 1975

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