Abstract
Purpose: To explore the association between the consumption of fruits and vegetables and the presence of glaucoma. Design: Cross-sectional cohort study. Methods: In a sample of 1,155 women located in multiple centers in the United States, glaucoma specialists diagnosed glaucoma in at least one eye by assessing optic nerve head photographs and 76-point suprathreshold screening visual fields. Consumption of fruits and vegetables was assessed using the Block Food Frequency Questionnaire. The relationship between selected fruit and vegetable consumption and glaucoma was investigated using adjusted logistic regression models. Results: Among 1,155 women, 95 (8.2%) were diagnosed with glaucoma. In adjusted analysis, the odds of glaucoma risk were decreased by 69% (odds ratio [OR], 0.31; 95% confidence interval [CI], 0.11 to 0.91) in women who consumed at least one serving per month of green collards and kale compared with those who consumed fewer than one serving per month, by 64% (OR, 0.36; 95% CI, 0.17 to 0.77) in women who consumed more than two servings per week of carrots compared with those who consumed fewer than one serving per week, and by 47% (OR, 0.53; 95% CI, 0.29 to 0.97) in women who consumed at least one serving per week of canned or dried peaches compared with those who consumed fewer than one serving per month. Conclusions: A higher intake of certain fruits and vegetables may be associated with a decreased risk of glaucoma. More studies are needed to investigate this relationship.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1081-1089 |
| Number of pages | 9 |
| Journal | American journal of ophthalmology |
| Volume | 145 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 2008 |
Bibliographical note
Funding Information:This study was supported by Research to Prevent Blindness, Inc, New York, New York, and the Gerald Oppenheimer Foundation Center for the Prevention of Eye Diseases, Los Angeles, California. Dr Mangione was supported by Grant AG-02-004 from the National Institutes of Health, National Institute of Aging, Bethesda, Maryland, to the UCLA Center for Health Improvement in Minority Elders/Resource Centers for Minority Aging Research. The Study of Osteoporotic Fractures is supported by Public Health Service Research Grants AG05407, AR35582, AG05394, AR35584, AR35583, R01AG005407, R01AG027576-22, 2 R01AG005394-22A1, and 2 R01AG027574-22A1 from the National Institutes of Health, Bethesda, Maryland. The authors indicate no financial conflict of interest. Involved in design of study (A.L.C., K.L.S., F.Y., K.E.E., J.A.C., M.C.H., C.M.M.); data collection (A.L.C., K.L.S., F.Y., K.L.P., K.E.E., J.A.C., M.C.H., F.T., F.B., C.M.M.); data management and analysis (A.L.C., K.L.S., F.Y., C.M.M.); data interpretation, preparation, review, and approval of manuscript (A.L.C., K.L.S., G.K., F.Y., K.L.P., K.E.E., J.A.C., M.C.H., F.T., F.B., C.M.M.). Institutional review board approvals were obtained from each participating institution, including the UCLA, Los Angeles, California; the California Pacific Medical Center Research Institute, San Francisco, California; The Kaiser Foundation Research Institute and Kaiser Permanente Center for Health Research, Portland, Oregon; the University of Minnesota, Minneapolis, Minnesota; the University of Pittsburgh, Pittsburgh, Pennsylvania; and the University of Maryland, Baltimore, Maryland, before the study commenced.