Abstract
Although the molecular mechanisms by which plants respond to gibberellins are largely unknown, several components of the signal transduction pathway have been identified and a broad outline of how these components act in signal transduction is emerging. One component of the pathway, SPINDLY, is believed to be an O-GlcNAc transferase that post-translationally modifies cytosolic and nuclear proteins by the addition of O-linked N-acetylglucosamine. Although analysis of the properties of O-GlcNAc-modified proteins from animals has led to the hypothesis that this modification is regulatory, it has not been linked to specific signal transduction pathways.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 424-428 |
| Number of pages | 5 |
| Journal | Trends in Plant Science |
| Volume | 4 |
| Issue number | 11 |
| DOIs | |
| State | Published - Nov 1 1999 |
Bibliographical note
Funding Information:This work was supported by a grant from the National Science Foundation (MCB-9604126). We thank Tong-Seung Tseng and Lynn Hartweck for helpful suggestions.
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