Gestational trophoblastic disease

Elizabeth L. Dickson, Sally A Mullany

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


Gestational trophoblastic disease (GTD) is a term that encompasses a spectrum of disorders all arising from the placenta, and specifically, from the villous trophoblast of the placenta. These diseases include hydatidiform mole (both complete and partial), invasive mole, choriocarcinoma (CCA), and placental site trophoblastic tumor (PSTT). The term gestational trophoblastic neoplasia (GTN) includes the disorders of invasive mole, CCA, and PSTT, as they have significant clinical impact. While in the past, this spectrum of diseases was known to have serious morbidity and mortality, with current diagnosis and treatment, cure rates are quoted to upwards of 98 % (Sebire and Seckle, BMJ 227:A1193, 2008). In this chapter, diagnosis, staging, and management of gestational trophoblastic disease are discussed.

Original languageEnglish (US)
Title of host publicationGynecologic Oncology
Subtitle of host publicationA Pocketbook
PublisherSpringer New York
Number of pages27
ISBN (Electronic)9781493919765
ISBN (Print)9781493919758
StatePublished - Jan 1 2015

Bibliographical note

Publisher Copyright:
© Springer Science+Business Media New York 2015.


  • Choriocarcinoma
  • Hydatidiform mole
  • Invasive mole
  • Placental site trophoblastic tumor


Dive into the research topics of 'Gestational trophoblastic disease'. Together they form a unique fingerprint.

Cite this