Gestational trophoblastic disease

Elizabeth L. Dickson, Sally A Mullany

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

Gestational trophoblastic disease (GTD) is a term that encompasses a spectrum of disorders all arising from the placenta, and specifically, from the villous trophoblast of the placenta. These diseases include hydatidiform mole (both complete and partial), invasive mole, choriocarcinoma (CCA), and placental site trophoblastic tumor (PSTT). The term gestational trophoblastic neoplasia (GTN) includes the disorders of invasive mole, CCA, and PSTT, as they have significant clinical impact. While in the past, this spectrum of diseases was known to have serious morbidity and mortality, with current diagnosis and treatment, cure rates are quoted to upwards of 98 % (Sebire and Seckle, BMJ 227:A1193, 2008). In this chapter, diagnosis, staging, and management of gestational trophoblastic disease are discussed.

Original languageEnglish (US)
Title of host publicationGynecologic Oncology
Subtitle of host publicationA Pocketbook
PublisherSpringer New York
Pages175-201
Number of pages27
ISBN (Electronic)9781493919765
ISBN (Print)9781493919758
DOIs
StatePublished - Jan 1 2015

Keywords

  • Choriocarcinoma
  • Hydatidiform mole
  • Invasive mole
  • Placental site trophoblastic tumor

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