Genomic features of Mycobacterium avium subsp. hominissuis isolated from pigs in Japan

Tetsuya Komatsu; Kenji Ohya; Atsushi Ota; Yukiko Nishiuchi; Hirokazu Yano; Kayoko Matsuo; Justice Opare Odoi; Shota Suganuma; Kotaro Sawai; Akemi Hasebe; Tetsuo Asai; Tokuma Yanai; Hideto Fukushi; Takayuki Wada; Shiomi Yoshida; Toshihiro Ito; Kentaro Arikawa; Mikihiko Kawai; Manabu Ato; Anthony D. Baughn; Tomotada Iwamoto; Fumito Maruyama

doi:10.46471/gigabyte.33

Genomic features of Mycobacterium avium subsp. hominissuis isolated from pigs in Japan

Tetsuya Komatsu, Kenji Ohya, Atsushi Ota, Yukiko Nishiuchi, Hirokazu Yano, Kayoko Matsuo, Justice Opare Odoi, Shota Suganuma, Kotaro Sawai, Akemi Hasebe, Tetsuo Asai, Tokuma Yanai, Hideto Fukushi, Takayuki Wada, Shiomi Yoshida, Toshihiro Ito, Kentaro Arikawa, Mikihiko Kawai, Manabu Ato, Anthony D. BaughnTomotada Iwamoto, Fumito Maruyama

Microbiology

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Mycobacterium avium subsp. hominissuis (MAH) is one of the most important agents causing non-tuberculosis mycobacterial infection in humans and pigs. There have been advances in genome analysis of MAH from human isolates, but studies of isolates from pigs are limited despite its potential source of infection to human. Here, we obtained 30 draft genome sequences of MAH from pigs reared in Japan. The 30 draft genomes were 4,848,678-5,620,788 bp in length, comprising 4652-5388 coding genes and 46-75 (median: 47) tRNAs. All isolates had restriction modification-associated genes and 185-222 predicted virulence genes. Two isolates had tRNA arrays and one isolate had a clustered regularly interspaced short palindromic repeat (CRISPR) region. Our results will be useful for evaluation of the ecology of MAH by providing a foundation for genome-based epidemiological studies.

Original language	English (US)
Article number	33
Journal	GigaByte
Volume	2021
DOIs	https://doi.org/10.46471/gigabyte.33
State	Published - Nov 12 2021

Bibliographical note

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© 2021 GigaScience Press. All Rights Reserved.

Keywords

Microbial Ecology
Microbiology
Molecular Genetics

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.46471/gigabyte.33

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Komatsu, T., Ohya, K., Ota, A., Nishiuchi, Y., Yano, H., Matsuo, K., Odoi, J. O., Suganuma, S., Sawai, K., Hasebe, A., Asai, T., Yanai, T., Fukushi, H., Wada, T., Yoshida, S., Ito, T., Arikawa, K., Kawai, M., Ato, M., ... Maruyama, F. (2021). Genomic features of Mycobacterium avium subsp. hominissuis isolated from pigs in Japan. GigaByte, 2021, Article 33. https://doi.org/10.46471/gigabyte.33

Komatsu, T, Ohya, K, Ota, A, Nishiuchi, Y, Yano, H, Matsuo, K, Odoi, JO, Suganuma, S, Sawai, K, Hasebe, A, Asai, T, Yanai, T, Fukushi, H, Wada, T, Yoshida, S, Ito, T, Arikawa, K, Kawai, M, Ato, M, Baughn, AD, Iwamoto, T & Maruyama, F 2021, 'Genomic features of Mycobacterium avium subsp. hominissuis isolated from pigs in Japan', GigaByte, vol. 2021, 33. https://doi.org/10.46471/gigabyte.33

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abstract = "Mycobacterium avium subsp. hominissuis (MAH) is one of the most important agents causing non-tuberculosis mycobacterial infection in humans and pigs. There have been advances in genome analysis of MAH from human isolates, but studies of isolates from pigs are limited despite its potential source of infection to human. Here, we obtained 30 draft genome sequences of MAH from pigs reared in Japan. The 30 draft genomes were 4,848,678-5,620,788 bp in length, comprising 4652-5388 coding genes and 46-75 (median: 47) tRNAs. All isolates had restriction modification-associated genes and 185-222 predicted virulence genes. Two isolates had tRNA arrays and one isolate had a clustered regularly interspaced short palindromic repeat (CRISPR) region. Our results will be useful for evaluation of the ecology of MAH by providing a foundation for genome-based epidemiological studies.",

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author = "Tetsuya Komatsu and Kenji Ohya and Atsushi Ota and Yukiko Nishiuchi and Hirokazu Yano and Kayoko Matsuo and Odoi, {Justice Opare} and Shota Suganuma and Kotaro Sawai and Akemi Hasebe and Tetsuo Asai and Tokuma Yanai and Hideto Fukushi and Takayuki Wada and Shiomi Yoshida and Toshihiro Ito and Kentaro Arikawa and Mikihiko Kawai and Manabu Ato and Baughn, {Anthony D.} and Tomotada Iwamoto and Fumito Maruyama",

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T1 - Genomic features of Mycobacterium avium subsp. hominissuis isolated from pigs in Japan

AU - Komatsu, Tetsuya

AU - Ohya, Kenji

AU - Ota, Atsushi

AU - Nishiuchi, Yukiko

AU - Yano, Hirokazu

AU - Matsuo, Kayoko

AU - Odoi, Justice Opare

AU - Suganuma, Shota

AU - Sawai, Kotaro

AU - Hasebe, Akemi

AU - Asai, Tetsuo

AU - Yanai, Tokuma

AU - Fukushi, Hideto

AU - Wada, Takayuki

AU - Yoshida, Shiomi

AU - Ito, Toshihiro

AU - Arikawa, Kentaro

AU - Kawai, Mikihiko

AU - Ato, Manabu

AU - Baughn, Anthony D.

AU - Iwamoto, Tomotada

AU - Maruyama, Fumito

PY - 2021/11/12

Y1 - 2021/11/12

N2 - Mycobacterium avium subsp. hominissuis (MAH) is one of the most important agents causing non-tuberculosis mycobacterial infection in humans and pigs. There have been advances in genome analysis of MAH from human isolates, but studies of isolates from pigs are limited despite its potential source of infection to human. Here, we obtained 30 draft genome sequences of MAH from pigs reared in Japan. The 30 draft genomes were 4,848,678-5,620,788 bp in length, comprising 4652-5388 coding genes and 46-75 (median: 47) tRNAs. All isolates had restriction modification-associated genes and 185-222 predicted virulence genes. Two isolates had tRNA arrays and one isolate had a clustered regularly interspaced short palindromic repeat (CRISPR) region. Our results will be useful for evaluation of the ecology of MAH by providing a foundation for genome-based epidemiological studies.

AB - Mycobacterium avium subsp. hominissuis (MAH) is one of the most important agents causing non-tuberculosis mycobacterial infection in humans and pigs. There have been advances in genome analysis of MAH from human isolates, but studies of isolates from pigs are limited despite its potential source of infection to human. Here, we obtained 30 draft genome sequences of MAH from pigs reared in Japan. The 30 draft genomes were 4,848,678-5,620,788 bp in length, comprising 4652-5388 coding genes and 46-75 (median: 47) tRNAs. All isolates had restriction modification-associated genes and 185-222 predicted virulence genes. Two isolates had tRNA arrays and one isolate had a clustered regularly interspaced short palindromic repeat (CRISPR) region. Our results will be useful for evaluation of the ecology of MAH by providing a foundation for genome-based epidemiological studies.

KW - Microbial Ecology

KW - Microbiology

KW - Molecular Genetics

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SN - 2709-4715

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M1 - 33

ER -

Genomic features of Mycobacterium avium subsp. hominissuis isolated from pigs in Japan

Abstract

Bibliographical note

Keywords

UN SDGs

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