Genome-wide patterns of genetic variation among elite maize inbred lines

Jinsheng Lai; Ruiqiang Li; Xun Xu; Weiwei Jin; Mingliang Xu; Hainan Zhao; Zhongkai Xiang; Weibin Song; Kai Ying; Mei Zhang; Yinping Jiao; Peixiang Ni; Jianguo Zhang; Dong Li; Xiaosen Guo; Kaixiong Ye; Min Jian; Bo Wang; Huisong Zheng; Huiqing Liang; Xiuqing Zhang; Shoucai Wang; Shaojiang Chen; Jiansheng Li; Yan Fu; Nathan M. Springer; Huanming Yang; Jian Wang; Jingrui Dai; Patrick S. Schnable; Jun Wang

doi:10.1038/ng.684

Genome-wide patterns of genetic variation among elite maize inbred lines

Jinsheng Lai
, Ruiqiang Li
, Xun Xu
, Weiwei Jin
, Mingliang Xu
, Hainan Zhao
, Zhongkai Xiang
, Weibin Song
, Kai Ying
, Mei Zhang
, Yinping Jiao
, Peixiang Ni
, Jianguo Zhang
, Dong Li
, Xiaosen Guo
, Kaixiong Ye
, Min Jian
, Bo Wang
, Huisong Zheng
, Huiqing Liang

Xiuqing Zhang, Shoucai Wang, Shaojiang Chen, Jiansheng Li, Yan Fu, Nathan M. Springer, Huanming Yang, Jian Wang, Jingrui Dai, Patrick S. Schnable, Jun Wang

Research output: Contribution to journal › Article › peer-review

430 Scopus citations

Abstract

We have resequenced a group of six elite maize inbred lines, including the parents of the most productive commercial hybrid in China. This effort uncovered more than 1,000,000 SNPs, 30,000 indel polymorphisms and 101 low-sequence-diversity chromosomal intervals in the maize genome. We also identified several hundred complete genes that show presence/absence variation among these resequenced lines. We discuss the potential roles of complementation of presence/absence variations and other deleterious mutations in contributing to heterosis. High-density SNP and indel polymorphism markers reported here are expected to be a valuable resource for future genetic studies and the molecular breeding of this important crop.

Original language	English (US)
Pages (from-to)	1027-1030
Number of pages	4
Journal	Nature Genetics
Volume	42
Issue number	11
DOIs	https://doi.org/10.1038/ng.684
State	Published - Nov 2010
Externally published	Yes

Bibliographical note

Funding Information:
Supported by the 973 program (2009CB118400; 2007CB815703; 2007CB815705; 2007CB109000), the 863 project (2010AA10A106), the National Natural Science Foundation of China (30725008), the Shenzhen Bureau of Science Technology & Information, China (ZYC200903240077A; CXB200903110066A), the Chinese Academy of Science (GJHZ0701-6), the Ole Rømer grant from the Danish

Funding Information:
Natural Science Research Council and the US National Science Foundation (DBI-0527192). We thank L. Goodman for editing the manuscript.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 2 Zero Hunger

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Lai, J, Li, R, Xu, X, Jin, W, Xu, M, Zhao, H, Xiang, Z, Song, W, Ying, K, Zhang, M, Jiao, Y, Ni, P, Zhang, J, Li, D, Guo, X, Ye, K, Jian, M, Wang, B, Zheng, H, Liang, H, Zhang, X, Wang, S, Chen, S, Li, J, Fu, Y, Springer, NM, Yang, H, Wang, J, Dai, J, Schnable, PS & Wang, J 2010, 'Genome-wide patterns of genetic variation among elite maize inbred lines', Nature Genetics, vol. 42, no. 11, pp. 1027-1030. https://doi.org/10.1038/ng.684

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title = "Genome-wide patterns of genetic variation among elite maize inbred lines",

abstract = "We have resequenced a group of six elite maize inbred lines, including the parents of the most productive commercial hybrid in China. This effort uncovered more than 1,000,000 SNPs, 30,000 indel polymorphisms and 101 low-sequence-diversity chromosomal intervals in the maize genome. We also identified several hundred complete genes that show presence/absence variation among these resequenced lines. We discuss the potential roles of complementation of presence/absence variations and other deleterious mutations in contributing to heterosis. High-density SNP and indel polymorphism markers reported here are expected to be a valuable resource for future genetic studies and the molecular breeding of this important crop.",

author = "Jinsheng Lai and Ruiqiang Li and Xun Xu and Weiwei Jin and Mingliang Xu and Hainan Zhao and Zhongkai Xiang and Weibin Song and Kai Ying and Mei Zhang and Yinping Jiao and Peixiang Ni and Jianguo Zhang and Dong Li and Xiaosen Guo and Kaixiong Ye and Min Jian and Bo Wang and Huisong Zheng and Huiqing Liang and Xiuqing Zhang and Shoucai Wang and Shaojiang Chen and Jiansheng Li and Yan Fu and Springer, \{Nathan M.\} and Huanming Yang and Jian Wang and Jingrui Dai and Schnable, \{Patrick S.\} and Jun Wang",

note = "Funding Information: Supported by the 973 program (2009CB118400; 2007CB815703; 2007CB815705; 2007CB109000), the 863 project (2010AA10A106), the National Natural Science Foundation of China (30725008), the Shenzhen Bureau of Science Technology \& Information, China (ZYC200903240077A; CXB200903110066A), the Chinese Academy of Science (GJHZ0701-6), the Ole R{\o}mer grant from the Danish Funding Information: Natural Science Research Council and the US National Science Foundation (DBI-0527192). We thank L. Goodman for editing the manuscript.",

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doi = "10.1038/ng.684",

language = "English (US)",

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AU - Lai, Jinsheng

AU - Li, Ruiqiang

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AU - Jin, Weiwei

AU - Xu, Mingliang

AU - Zhao, Hainan

AU - Xiang, Zhongkai

AU - Song, Weibin

AU - Ying, Kai

AU - Zhang, Mei

AU - Jiao, Yinping

AU - Ni, Peixiang

AU - Zhang, Jianguo

AU - Li, Dong

AU - Guo, Xiaosen

AU - Ye, Kaixiong

AU - Jian, Min

AU - Wang, Bo

AU - Zheng, Huisong

AU - Liang, Huiqing

AU - Zhang, Xiuqing

AU - Wang, Shoucai

AU - Chen, Shaojiang

AU - Li, Jiansheng

AU - Fu, Yan

AU - Springer, Nathan M.

AU - Yang, Huanming

AU - Wang, Jian

AU - Dai, Jingrui

AU - Schnable, Patrick S.

AU - Wang, Jun

N1 - Funding Information: Supported by the 973 program (2009CB118400; 2007CB815703; 2007CB815705; 2007CB109000), the 863 project (2010AA10A106), the National Natural Science Foundation of China (30725008), the Shenzhen Bureau of Science Technology & Information, China (ZYC200903240077A; CXB200903110066A), the Chinese Academy of Science (GJHZ0701-6), the Ole Rømer grant from the Danish Funding Information: Natural Science Research Council and the US National Science Foundation (DBI-0527192). We thank L. Goodman for editing the manuscript.

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N2 - We have resequenced a group of six elite maize inbred lines, including the parents of the most productive commercial hybrid in China. This effort uncovered more than 1,000,000 SNPs, 30,000 indel polymorphisms and 101 low-sequence-diversity chromosomal intervals in the maize genome. We also identified several hundred complete genes that show presence/absence variation among these resequenced lines. We discuss the potential roles of complementation of presence/absence variations and other deleterious mutations in contributing to heterosis. High-density SNP and indel polymorphism markers reported here are expected to be a valuable resource for future genetic studies and the molecular breeding of this important crop.

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Genome-wide patterns of genetic variation among elite maize inbred lines

Abstract

Bibliographical note

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