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Genome-wide interrogation of longitudinal FEV
1
in children with asthma
Kehua Wu
, Eric R. Gamazon
, Hae Kyung Im
, Paul Geeleher
, Steven R. White
, Julian Solway
, George L. Clemmer
, Scott T. Weiss
, Kelan G. Tantisira
, Nancy J. Cox
, Mark J. Ratain
,
R. Stephanie Huang
Experimental and Clinical Pharmacology
Research output
:
Contribution to journal
›
Article
›
peer-review
19
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Scopus citations
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1
in children with asthma'. Together they form a unique fingerprint.
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Keyphrases
Forced Expiratory Volume in 1 Second (FEV1)
100%
Children with Asthma
100%
Lung Function
66%
Placebo
66%
Single nucleotide Polymorphism
66%
Nedocromil
66%
Longitudinal Traits
66%
Childhood Asthma Management Program
66%
Gene Expression
33%
Genetic Determinants
33%
Genome-wide Association Study
33%
Potential Treatments
33%
Lung Function Decline
33%
Asthma
33%
Population-based
33%
Chronic Disease
33%
Targeted Treatment
33%
Genetic Mapping
33%
Presence-absence
33%
NONMEM
33%
Chromatin Immunoprecipitation (ChIP)
33%
Phenotypic Data
33%
Human Lung Tissue
33%
Progression Model
33%
False Discovery Rate
33%
Human Lung Fibroblasts
33%
Lung Fibroblasts
33%
RNA-seq Data
33%
Budesonide
33%
Disease Pathophysiology
33%
Enhancer Region
33%
Strong Enhancer
33%
Dynamic Progress
33%
Single Time Point
33%
Longitudinal Progression
33%
Exponential Structure
33%
Biochemistry, Genetics and Molecular Biology
Genetics
100%
Single-Nucleotide Polymorphism
100%
Enhancer Region
100%
Fibroblast
100%
RNA Sequencing
50%
Gene Expression
50%
Genome-Wide Association Study
50%
Gene Mapping
50%
Budesonide
50%
Immunology and Microbiology
Asthma
100%
Nedocromil
33%
Single Nucleotide Polymorphism
33%
Enhancer Region
33%
Lung Fibroblast
33%
RNA Sequencing
16%
Gene Expression
16%
Genome-Wide Association Study
16%
Gene Mapping
16%
Budesonide
16%
Replication
16%