Genome characterization of Turkey rotavirus G strains from the United States identifies potential recombination events with human rotavirus B strains

Fangzhou Chen; Todd P. Knutson; Robert E. Porter; Max Ciarlet; Sunil Kumar Mor; Douglas G. Marthaler

doi:10.1099/jgv.0.000963

Genome characterization of Turkey rotavirus G strains from the United States identifies potential recombination events with human rotavirus B strains

Fangzhou Chen, Todd P. Knutson, Robert E. Porter, Max Ciarlet, Sunil Kumar Mor, Douglas G. Marthaler

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Rotavirus G (RVG) strains have been detected in a variety of avian species, but RVG genomes have been published from only a single pigeon and two chicken strains. Two turkey RVG strains were identified and characterized, one in a hatchery with no reported health issues and the other in a hatchery with high embryo/poult mortality. The two turkey RVG strains shared only an 85.3 % nucleotide sequence identity in the VP7 gene while the other genes possessed high nucleotide identity among them (96.3-99.9 %). Low nucleotide percentage identities (31.6-87.3 %) occurred among the pigeon and chicken RVG strains. Interestingly, potential recombination events were detected between our RVG strains and a human RVB strain, in the VP6 and NSP3 segments. The epidemiology of RVG in avian flocks and the pathogenicity of the two different RVG strains should be further investigated to understand the ecology and impact of RVG in commercial poultry flocks.

Original language	English (US)
Article number	000963
Pages (from-to)	2931-2936
Number of pages	6
Journal	Journal of General Virology
Volume	98
Issue number	12
DOIs	https://doi.org/10.1099/jgv.0.000963
State	Published - Dec 2017

Bibliographical note

Funding Information:
This study was supported by the University of Minnesota Veterinary Diagnostic Laboratory. Fangzhou Chen was supported by the China Agriculture Research System (No. CARS-36) and China Scholarship Council No. 201606760012.

Publisher Copyright:
© 2017 The Authors.

Keywords

Phylogenetic
Rotavirus G

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Publisher link

10.1099/jgv.0.000963

Find It

Find It at U of M Libraries

Cite this

@article{2c50083f55714e9fad78490d6a2b5bf6,

title = "Genome characterization of Turkey rotavirus G strains from the United States identifies potential recombination events with human rotavirus B strains",

abstract = "Rotavirus G (RVG) strains have been detected in a variety of avian species, but RVG genomes have been published from only a single pigeon and two chicken strains. Two turkey RVG strains were identified and characterized, one in a hatchery with no reported health issues and the other in a hatchery with high embryo/poult mortality. The two turkey RVG strains shared only an 85.3 % nucleotide sequence identity in the VP7 gene while the other genes possessed high nucleotide identity among them (96.3-99.9 %). Low nucleotide percentage identities (31.6-87.3 %) occurred among the pigeon and chicken RVG strains. Interestingly, potential recombination events were detected between our RVG strains and a human RVB strain, in the VP6 and NSP3 segments. The epidemiology of RVG in avian flocks and the pathogenicity of the two different RVG strains should be further investigated to understand the ecology and impact of RVG in commercial poultry flocks.",

keywords = "Phylogenetic, Rotavirus G",

author = "Fangzhou Chen and Knutson, {Todd P.} and Porter, {Robert E.} and Max Ciarlet and Mor, {Sunil Kumar} and Marthaler, {Douglas G.}",

note = "Funding Information: This study was supported by the University of Minnesota Veterinary Diagnostic Laboratory. Fangzhou Chen was supported by the China Agriculture Research System (No. CARS-36) and China Scholarship Council No. 201606760012. Publisher Copyright: {\textcopyright} 2017 The Authors.",

year = "2017",

month = dec,

doi = "10.1099/jgv.0.000963",

language = "English (US)",

volume = "98",

pages = "2931--2936",

journal = "Journal of General Virology",

issn = "0022-1317",

publisher = "Society for General Microbiology",

number = "12",

}

TY - JOUR

T1 - Genome characterization of Turkey rotavirus G strains from the United States identifies potential recombination events with human rotavirus B strains

AU - Chen, Fangzhou

AU - Knutson, Todd P.

AU - Porter, Robert E.

AU - Ciarlet, Max

AU - Mor, Sunil Kumar

AU - Marthaler, Douglas G.

N1 - Funding Information: This study was supported by the University of Minnesota Veterinary Diagnostic Laboratory. Fangzhou Chen was supported by the China Agriculture Research System (No. CARS-36) and China Scholarship Council No. 201606760012. Publisher Copyright: © 2017 The Authors.

PY - 2017/12

Y1 - 2017/12

N2 - Rotavirus G (RVG) strains have been detected in a variety of avian species, but RVG genomes have been published from only a single pigeon and two chicken strains. Two turkey RVG strains were identified and characterized, one in a hatchery with no reported health issues and the other in a hatchery with high embryo/poult mortality. The two turkey RVG strains shared only an 85.3 % nucleotide sequence identity in the VP7 gene while the other genes possessed high nucleotide identity among them (96.3-99.9 %). Low nucleotide percentage identities (31.6-87.3 %) occurred among the pigeon and chicken RVG strains. Interestingly, potential recombination events were detected between our RVG strains and a human RVB strain, in the VP6 and NSP3 segments. The epidemiology of RVG in avian flocks and the pathogenicity of the two different RVG strains should be further investigated to understand the ecology and impact of RVG in commercial poultry flocks.

AB - Rotavirus G (RVG) strains have been detected in a variety of avian species, but RVG genomes have been published from only a single pigeon and two chicken strains. Two turkey RVG strains were identified and characterized, one in a hatchery with no reported health issues and the other in a hatchery with high embryo/poult mortality. The two turkey RVG strains shared only an 85.3 % nucleotide sequence identity in the VP7 gene while the other genes possessed high nucleotide identity among them (96.3-99.9 %). Low nucleotide percentage identities (31.6-87.3 %) occurred among the pigeon and chicken RVG strains. Interestingly, potential recombination events were detected between our RVG strains and a human RVB strain, in the VP6 and NSP3 segments. The epidemiology of RVG in avian flocks and the pathogenicity of the two different RVG strains should be further investigated to understand the ecology and impact of RVG in commercial poultry flocks.

KW - Phylogenetic

KW - Rotavirus G

UR - http://www.scopus.com/inward/record.url?scp=85038223463&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85038223463&partnerID=8YFLogxK

U2 - 10.1099/jgv.0.000963

DO - 10.1099/jgv.0.000963

M3 - Article

C2 - 29168675

AN - SCOPUS:85038223463

SN - 0022-1317

VL - 98

SP - 2931

EP - 2936

JO - Journal of General Virology

JF - Journal of General Virology

IS - 12

M1 - 000963

ER -

Genome characterization of Turkey rotavirus G strains from the United States identifies potential recombination events with human rotavirus B strains

Abstract

Bibliographical note

Keywords

UN SDGs

Publisher link

Find It

Other files and links

Fingerprint

Cite this