Genetics of nickel allergic contact dermatitis

Sarah E. Schram, Erin M. Warshaw

Research output: Contribution to journalReview articlepeer-review

25 Scopus citations


Nickel sulfate is the most frequently detected cause of allergic contact dermatitis in the world; the prevalence of nickel allergic contact dermatitis is between 8 and 11% in the general female population. Although it is well recognized that environmental factors are important in the pathogenesis of this dermatitis, some investigators have hypothesized that genetic factors are important as well. This review summarizes animal and human studies evaluating genetic factors in the development of allergic contact dermatitis from nickel.

Original languageEnglish (US)
Pages (from-to)125-133
Number of pages9
Issue number3
StatePublished - Sep 1 2007


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