Genetically predicted circulating levels of copper and zinc are associated with osteoarthritis but not with rheumatoid arthritis

Keyphrases

• Rheumatoid Arthritis 100%
• Osteoarthritis 100%
• Zinc 100%
• Circulating Levels 100%
• Single nucleotide Polymorphism 16%
• Copper Status 16%
• Zinc Status 16%
• Genome-wide Association Study 8%
• Magnesium-zinc-yttrium 8%
• Disability 8%
• Copper-iron 8%
• Prevention Strategies 8%
• Causal Effect 8%
• European Ancestry 8%
• Sensitivity Analysis 8%
• Pleiotropy 8%
• Zinc-copper 8%
• Large Genome 8%
• Blood Levels 8%
• Mineral Status 8%
• Mendelian Randomization Analysis 8%
• UK Biobank 8%
• Genetic Instruments 8%
• Biobank Participants 8%
• Osteoarthritis Prevention 8%
• Generalized Osteoarthritis 8%
• Debilitating Disease 8%
• High-purity Zinc 8%
• Minerals Level 8%

Biochemistry, Genetics and Molecular Biology

• Zinc 100%
• Single-Nucleotide Polymorphism 66%
• Genetics 33%
• Mendelian Randomization 33%
• Pleiotropy 33%
• Blood Level 33%
• Genome-Wide Association Study 33%

Food Science

• Magnesium 100%