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Genetic variation in F3 (tissue factor) and the risk of incident venous thrombosis: Meta-analysis of eight studies

  • N. L. Smith
  • , J. A. Heit
  • , W. Tang
  • , M. Teichert
  • , D. I. Chasman
  • , P. E. Morange
  • , B. McKnight
  • , N. Pankratz
  • , F. W G Leebeek
  • , L. M. Rose
  • , P. Amouyel
  • , A. G. Uitterlinden
  • , A. Hofman
  • , M. Lathrop
  • , J. C. Lambert
  • , M. Cushman
  • , M. De Andrade
  • , A. R. Folsom
  • , B. H. Stricker
  • , P. M. Ridker
  • D. A. Tregouet

Research output: Contribution to journalLetterpeer-review

Original languageEnglish (US)
Pages (from-to)719-722
Number of pages4
JournalJournal of Thrombosis and Haemostasis
Volume10
Issue number4
DOIs
StatePublished - Apr 2012

Bibliographical note

Funding Information:
The Longitudinal Investigation of Thromboembolism Etiology was funded by National Heart, Lung and Blood Institute grant R01 HL59367. Within LITE, the ARIC study was funded by NHLBI contracts N01‐HC‐55015, N01‐HC‐55016, N01‐HC‐55018, N01‐HC‐55019, N01‐HC‐55020, N01‐HC‐55021 and N01‐HC‐55022 and the CHS research was supported by NHLBI contracts N01‐HC‐85239, N01‐HC‐85079 through to N01‐HC‐85086, N01‐HC‐35129, N01 HC‐15103, N01 HC‐55222, N01‐HC‐75150, N01‐HC‐45133 and NHLBI grants HL080295, HL075366, HL087652, HL105756 with additional contribution from NINDS. Additional support was provided through AG‐023629, AG‐15928, AG‐20098 and AG‐027058 from the NIA. DNA handling and genotyping was supported in part by National Center for Research Resources CTSI grant UL 1RR033176 and National Institute of Diabetes and Digestive and Kidney Diseases grant DK063491 to the Southern California Diabetes Endocrinology Research Center.

Funding Information:
The Women’s Genome Health Study is supported by HL043851 and HL69757 from the National Heart, Lung and Blood Institute and CA 047988 from the National Cancer Institute, the Donald W. Reynolds Foundation and the Fondation Leducq, with collaborative scientific support and funding for genotyping provided by Amgen

Funding Information:
The Rotterdam Study is supported by the Erasmus Medical Center and Erasmus University Rotterdam, The Netherlands Organization for Scientific Research (NWO), The Netherlands Organization for Health Research and Development (ZonMw), the Research Institute for Diseases in the Elderly (RIDE), The Netherlands Genomics Initiative, the Ministry of Education, Culture and Science, the Ministry of Health, Welfare and Sports, the European Commission (DG XII), and the Municipality of Rotterdam.

Funding Information:
The Heart and Vascular Health study is supported by the National Health Lung and Blood Institute grants HL43201, HL60739, HL68986, HL73410, HL74745, HL85251 and HL95080, and by a grant from the Leducq Foundation, Paris, France, for the development of Transatlantic Networks of Excellence in Cardiovascular Research.

Funding Information:
The Mayo VTE Study is funded, in part, by grants from the National Institutes of Health, National Heart, Lung and Blood Institute (HL83141) and National Human Genome Research Institute (HG04735), US Public Health Service, and by the Mayo Foundation.

Funding Information:
The EOVT and MARTHA projects were supported by a grant from the Program Hospitalier de Recherche Clinique. The 3C Study, which served as control group for the MARTHA project, was conducted under a partnership agreement between Inserm, the Victor Segalen – Bordeaux II University and Sanofi‐Synthélabo. The Fondation pour la Recherche Médicale funded the preparation and first phase of the study. The 3C Study is also supported by the Caisse Nationale Maladie des Travailleurs Salariés, Direction Générale de la Santé, Mutuelle Générale de l’Education Nationale, the Institut de la Longévité, Agence Française de Sécurité Sanitaire des Produits de Santé, the Regional Governments of Aquitaine, Bourgogne and Languedoc‐Roussillon and the Fondation de France, the Ministry of Research‐Inserm Programme ‘Cohorts and collection of biological material’. The Lille Génopôle received an unconditional grant from Eisai.

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