Genetic manipulation of sex ratio in mammals

the Reaper comes for Mickey

Research output: Contribution to journalComment/debate

Abstract

In most animals, sexual reproduction results in a 1:1 ratio of females to males. For several sectors of agriculture, for example, milk or egg production, only a single sex is needed. Biasing the sex ratio so that only offspring of the desired sex are produced has the potential to increase breeding efficiency. In this issue of EMBO Reports, Yosef et al [1] demonstrate a genetic approach to bias the sex ratio in mice by specifically disrupting essential genes in male embryos. Their approach is an important first step toward generating sex-ratio biasing applications for agriculture.

Original languageEnglish (US)
Article numbere48577
JournalEMBO Reports
Volume20
Issue number8
DOIs
StatePublished - Jan 1 2019

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Mammals
Sex Ratio
Agriculture
Animals
Genes
Essential Genes
Breeding
Reproduction
Ovum
Milk
Embryonic Structures

Cite this

Genetic manipulation of sex ratio in mammals : the Reaper comes for Mickey. / Smanski, Michael J; Zarkower, David A.

In: EMBO Reports, Vol. 20, No. 8, e48577, 01.01.2019.

Research output: Contribution to journalComment/debate

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