Genetic manipulation of sex ratio in mammals: the Reaper comes for Mickey

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Abstract

In most animals, sexual reproduction results in a 1:1 ratio of females to males. For several sectors of agriculture, for example, milk or egg production, only a single sex is needed. Biasing the sex ratio so that only offspring of the desired sex are produced has the potential to increase breeding efficiency. In this issue of EMBO Reports, Yosef et al [1] demonstrate a genetic approach to bias the sex ratio in mice by specifically disrupting essential genes in male embryos. Their approach is an important first step toward generating sex-ratio biasing applications for agriculture.

Original languageEnglish (US)
Article numbere48577
JournalEMBO Reports
Volume20
Issue number8
DOIs
StatePublished - Aug 2019

Bibliographical note

Publisher Copyright:
© 2019 The Authors

Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.

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