Genetic inactivation of calpain-1 attenuates pain sensitivity in a humanized mouse model of sickle cell disease

Jennifer O. Nwankwo; Jianxun Lei; Jian Xu; Alicia Rivera; Kalpna Gupta; Athar H. Chishti

doi:10.3324/haematol.2016.148106

Genetic inactivation of calpain-1 attenuates pain sensitivity in a humanized mouse model of sickle cell disease

Jennifer O. Nwankwo, Jianxun Lei, Jian Xu, Alicia Rivera, Kalpna Gupta, Athar H. Chishti

Medicine - Hematology, Oncology, Transplant

Research output: Contribution to journal › Letter › peer-review

12 Scopus citations

Original language	English (US)
Pages (from-to)	e397-e400
Journal	Haematologica
Volume	101
Issue number	10
DOIs	https://doi.org/10.3324/haematol.2016.148106
State	Published - Sep 30 2016

Keywords

Calpain-1
Genetic inactivation
Humanized mouse model
Pain
Sickle cell disease

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10.3324/haematol.2016.148106

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@article{73723fa99f9147348f6a959f4c09cc41,

title = "Genetic inactivation of calpain-1 attenuates pain sensitivity in a humanized mouse model of sickle cell disease",

keywords = "Calpain-1, Genetic inactivation, Humanized mouse model, Pain, Sickle cell disease",

author = "Nwankwo, {Jennifer O.} and Jianxun Lei and Jian Xu and Alicia Rivera and Kalpna Gupta and Chishti, {Athar H.}",

year = "2016",

month = sep,

day = "30",

doi = "10.3324/haematol.2016.148106",

language = "English (US)",

volume = "101",

pages = "e397--e400",

journal = "Haematologica",

issn = "0390-6078",

publisher = "Ferrata Storti Foundation",

number = "10",

}

TY - JOUR

T1 - Genetic inactivation of calpain-1 attenuates pain sensitivity in a humanized mouse model of sickle cell disease

AU - Nwankwo, Jennifer O.

AU - Lei, Jianxun

AU - Xu, Jian

AU - Rivera, Alicia

AU - Gupta, Kalpna

AU - Chishti, Athar H.

PY - 2016/9/30

Y1 - 2016/9/30

KW - Calpain-1

KW - Genetic inactivation

KW - Humanized mouse model

KW - Pain

KW - Sickle cell disease

UR - http://www.scopus.com/inward/record.url?scp=84989326343&partnerID=8YFLogxK

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U2 - 10.3324/haematol.2016.148106

DO - 10.3324/haematol.2016.148106

M3 - Letter

C2 - 27418647

AN - SCOPUS:84989326343

SN - 0390-6078

VL - 101

SP - e397-e400

JO - Haematologica

JF - Haematologica

IS - 10

ER -

Genetic inactivation of calpain-1 attenuates pain sensitivity in a humanized mouse model of sickle cell disease

Keywords

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