Genetic and environmental influences on anorexia nervosa syndromes in a population-based twin sample

K. L. Klump, K. B. Miller, P. K. Keel, M. McGue, W. G. Iacono

Research output: Contribution to journalArticlepeer-review

177 Scopus citations

Abstract

Background. Genetic and environmental influences on broadly-defined anorexia nervosa (AN) syndrome were examined in a population-based twin sample. Methods. AN syndrome was assessed in 672 female 17 year-old twins using structured interviews and a self-report questionnaire. Results. Twenty-six probands with AN syndrome were identified. Biometrical model-fitting analyses indicated that genetic and non-shared environmental factors accounted for 74% and 26% of the variance in AN syndrome, respectively. Conclusions. Findings support previous research indicating significant genetic and non-shared environmental influences on AN syndromes.

Original languageEnglish (US)
Pages (from-to)737-740
Number of pages4
JournalPsychological medicine
Volume31
Issue number4
DOIs
StatePublished - 2001

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