General aspects of fertility and infertility

Mark A. Damario

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Fertility rates have been declining in most Western nations over the past several decades, although it is not entirely clear if an increased rate of infertility substantially contributes to this. As compared to other species, the reproductive efficiency of humans is relatively low. Factors related to fertility include age, exposure to sexually transmitted diseases, frequency of intercourse, coital timing, as well as diet and lifestyle habits. Infertility is considered a disease due to its major disruption of major organ systems and life functions. An infertility evaluation is recommended after 12 months or more of regular, unprotected intercourse and may be considered after 6 months for those female patients over the age of 35 or with other known abnormalities. A proper infertility evaluation is a comprehensive examination of possibly identifiable infertility factors of both female and male partners, lending itself to the most appropriate and potentially effective treatment.

Original languageEnglish (US)
Pages (from-to)3-23
Number of pages21
JournalMethods in Molecular Biology
StatePublished - 2014

Bibliographical note

Publisher Copyright:
© Springer Science+Business Media New York 2014.


  • Causes of infertility
  • Cervical factor
  • Infertility
  • Male factor
  • Ovarian reserve
  • Ovulatory function
  • Peritoneal factor
  • Reproductive age
  • Tubal factor
  • Uterine factor


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