Gene therapy: Trials and tribulations

Nikunj Somia, Inder M. Verma

Research output: Contribution to journalReview articlepeer-review

524 Scopus citations

Abstract

The art and science of gene therapy has received much attention of late. The tragic death of 18-year-old Jesse Gelsinger, a volunteer in a Phase I clinical trial, has overshadowed the successful treatment of three children suffering from a rare but fatal immunological disease. In the light of the success and tragedy, it is timely to consider the challenges faced by gene therapy - a novel form of molecular medicine that may be poised to have an important impact on human health in the new millennium.

Original languageEnglish (US)
Pages (from-to)91-99
Number of pages9
JournalNature Reviews Genetics
Volume1
Issue number2
DOIs
StatePublished - Nov 2000

Fingerprint Dive into the research topics of 'Gene therapy: Trials and tribulations'. Together they form a unique fingerprint.

Cite this