Gene expression as a drug discovery tool

William E. Evans; R. Kip Guy

doi:10.1038/ng0304-214

Gene expression as a drug discovery tool

William E. Evans
, R. Kip Guy

Research output: Contribution to journal › Short survey › peer-review

33 Scopus citations

Abstract

After establishing a pattern of gene expression that identifies a desired drug effect in leukemia cells (e.g., differentiation), post-treatment gene expression can be used to screen candidate compounds for their ability to induce the target phenotype.

Original language	English (US)
Pages (from-to)	214-215
Number of pages	2
Journal	Nature Genetics
Volume	36
Issue number	3
DOIs	https://doi.org/10.1038/ng0304-214
State	Published - Mar 2004
Externally published	Yes

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10.1038/ng0304-214

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abstract = "After establishing a pattern of gene expression that identifies a desired drug effect in leukemia cells (e.g., differentiation), post-treatment gene expression can be used to screen candidate compounds for their ability to induce the target phenotype.",

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JO - Nature Genetics

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Gene expression as a drug discovery tool

Abstract

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