Abstract
Non-melanoma skin cancers (NMSCs) are the most common malignancy among US Caucasians. Using a population-based study of NMSC we found that oral steroid use is associated with nearly 6-fold elevated risk of squamous cell carcinoma among individuals with a common genetic variant in the steroid receptor (NR3C1) gene. Given the large numbers of individuals on immunosuppressive drug therapy for inflammatory disease, these findings have important implications for NMSC screening and prevention.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1868-1870 |
| Number of pages | 3 |
| Journal | Journal of Investigative Dermatology |
| Volume | 127 |
| Issue number | 8 |
| DOIs | |
| State | Published - Aug 2007 |
Bibliographical note
Funding Information:We are indebted to the NH Society of Dermatology and participating dermatologists for their collaboration. This study was supported by the National Cancer Institute Grants R01 CA 8354 and R01 CA 57494.
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
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