Gastrointestinal effects of resistant starch, soluble maize fibre and pullulan in healthy adults

Abby S. Klosterbuer, Meredith A.J. Hullar, Fei Li, Elizabeth Traylor, Johanna W. Lampe, William Thomas, Joanne L Slavin

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Fibre has been shown to exert a number of benefits on gastrointestinal (GI) health, yet its intake is low. Addition of novel fibres to food products may increase fibre intake and improve gut health. The objective of the present study was to evaluate the influence of three novel fibres on GI outcomes in healthy human subjects. A total of twenty healthy participants (ten men and ten women) with normal BMI (23 (sem 2)Â kg/m2) participated in the present randomised, double-blind, cross-over study with five treatment periods. Participants consumed a maltodextrin control or 20-25Â g/d fibre from soluble maize fibre (SCF) or resistant starch (RS), alone or in combination with pullulan (SCF+P and RS+P). The treatment periods were 7Â d with a 3-week washout between the periods. Stool samples were collected on day 7 of each period, and GI tolerance was assessed via a questionnaire on days 1 and 6. There were no treatment differences in stool weight or consistency. SCF significantly reduced stool pH and increased total SCFA production compared with RS and control. RS+P significantly increased the percentage of butyrate compared with all the other treatments. Overall, GI symptoms were minimal. SCF+P led to the highest GI score on day 1, while RS+P had the highest score on day 6. Both SCF treatments caused a significant shift in the gut microbial community. These functional fibres are generally well tolerated, have minimal effects on laxation and may lead to beneficial changes in SCFA production in healthy adults.

Original languageEnglish (US)
Pages (from-to)1068-1074
Number of pages7
JournalBritish Journal of Nutrition
Volume110
Issue number6
DOIs
StatePublished - Sep 28 2013

Fingerprint

Starch
Zea mays
Healthy Volunteers
Therapeutics
Butyrates
Health
Cross-Over Studies
pullulan
Weights and Measures
Food

Keywords

  • Butyrate
  • Fibre
  • Microbiota
  • Tolerance

Cite this

Gastrointestinal effects of resistant starch, soluble maize fibre and pullulan in healthy adults. / Klosterbuer, Abby S.; Hullar, Meredith A.J.; Li, Fei; Traylor, Elizabeth; Lampe, Johanna W.; Thomas, William; Slavin, Joanne L.

In: British Journal of Nutrition, Vol. 110, No. 6, 28.09.2013, p. 1068-1074.

Research output: Contribution to journalArticle

Klosterbuer, Abby S. ; Hullar, Meredith A.J. ; Li, Fei ; Traylor, Elizabeth ; Lampe, Johanna W. ; Thomas, William ; Slavin, Joanne L. / Gastrointestinal effects of resistant starch, soluble maize fibre and pullulan in healthy adults. In: British Journal of Nutrition. 2013 ; Vol. 110, No. 6. pp. 1068-1074.
@article{c8cb7bf9c0e445e9b490fd75290ad00a,
title = "Gastrointestinal effects of resistant starch, soluble maize fibre and pullulan in healthy adults",
abstract = "Fibre has been shown to exert a number of benefits on gastrointestinal (GI) health, yet its intake is low. Addition of novel fibres to food products may increase fibre intake and improve gut health. The objective of the present study was to evaluate the influence of three novel fibres on GI outcomes in healthy human subjects. A total of twenty healthy participants (ten men and ten women) with normal BMI (23 (sem 2){\^A} kg/m2) participated in the present randomised, double-blind, cross-over study with five treatment periods. Participants consumed a maltodextrin control or 20-25{\^A} g/d fibre from soluble maize fibre (SCF) or resistant starch (RS), alone or in combination with pullulan (SCF+P and RS+P). The treatment periods were 7{\^A} d with a 3-week washout between the periods. Stool samples were collected on day 7 of each period, and GI tolerance was assessed via a questionnaire on days 1 and 6. There were no treatment differences in stool weight or consistency. SCF significantly reduced stool pH and increased total SCFA production compared with RS and control. RS+P significantly increased the percentage of butyrate compared with all the other treatments. Overall, GI symptoms were minimal. SCF+P led to the highest GI score on day 1, while RS+P had the highest score on day 6. Both SCF treatments caused a significant shift in the gut microbial community. These functional fibres are generally well tolerated, have minimal effects on laxation and may lead to beneficial changes in SCFA production in healthy adults.",
keywords = "Butyrate, Fibre, Microbiota, Tolerance",
author = "Klosterbuer, {Abby S.} and Hullar, {Meredith A.J.} and Fei Li and Elizabeth Traylor and Lampe, {Johanna W.} and William Thomas and Slavin, {Joanne L}",
year = "2013",
month = "9",
day = "28",
doi = "10.1017/S0007114513000019",
language = "English (US)",
volume = "110",
pages = "1068--1074",
journal = "British Journal of Nutrition",
issn = "0007-1145",
publisher = "Cambridge University Press",
number = "6",

}

TY - JOUR

T1 - Gastrointestinal effects of resistant starch, soluble maize fibre and pullulan in healthy adults

AU - Klosterbuer, Abby S.

AU - Hullar, Meredith A.J.

AU - Li, Fei

AU - Traylor, Elizabeth

AU - Lampe, Johanna W.

AU - Thomas, William

AU - Slavin, Joanne L

PY - 2013/9/28

Y1 - 2013/9/28

N2 - Fibre has been shown to exert a number of benefits on gastrointestinal (GI) health, yet its intake is low. Addition of novel fibres to food products may increase fibre intake and improve gut health. The objective of the present study was to evaluate the influence of three novel fibres on GI outcomes in healthy human subjects. A total of twenty healthy participants (ten men and ten women) with normal BMI (23 (sem 2)Â kg/m2) participated in the present randomised, double-blind, cross-over study with five treatment periods. Participants consumed a maltodextrin control or 20-25Â g/d fibre from soluble maize fibre (SCF) or resistant starch (RS), alone or in combination with pullulan (SCF+P and RS+P). The treatment periods were 7Â d with a 3-week washout between the periods. Stool samples were collected on day 7 of each period, and GI tolerance was assessed via a questionnaire on days 1 and 6. There were no treatment differences in stool weight or consistency. SCF significantly reduced stool pH and increased total SCFA production compared with RS and control. RS+P significantly increased the percentage of butyrate compared with all the other treatments. Overall, GI symptoms were minimal. SCF+P led to the highest GI score on day 1, while RS+P had the highest score on day 6. Both SCF treatments caused a significant shift in the gut microbial community. These functional fibres are generally well tolerated, have minimal effects on laxation and may lead to beneficial changes in SCFA production in healthy adults.

AB - Fibre has been shown to exert a number of benefits on gastrointestinal (GI) health, yet its intake is low. Addition of novel fibres to food products may increase fibre intake and improve gut health. The objective of the present study was to evaluate the influence of three novel fibres on GI outcomes in healthy human subjects. A total of twenty healthy participants (ten men and ten women) with normal BMI (23 (sem 2)Â kg/m2) participated in the present randomised, double-blind, cross-over study with five treatment periods. Participants consumed a maltodextrin control or 20-25Â g/d fibre from soluble maize fibre (SCF) or resistant starch (RS), alone or in combination with pullulan (SCF+P and RS+P). The treatment periods were 7Â d with a 3-week washout between the periods. Stool samples were collected on day 7 of each period, and GI tolerance was assessed via a questionnaire on days 1 and 6. There were no treatment differences in stool weight or consistency. SCF significantly reduced stool pH and increased total SCFA production compared with RS and control. RS+P significantly increased the percentage of butyrate compared with all the other treatments. Overall, GI symptoms were minimal. SCF+P led to the highest GI score on day 1, while RS+P had the highest score on day 6. Both SCF treatments caused a significant shift in the gut microbial community. These functional fibres are generally well tolerated, have minimal effects on laxation and may lead to beneficial changes in SCFA production in healthy adults.

KW - Butyrate

KW - Fibre

KW - Microbiota

KW - Tolerance

UR - http://www.scopus.com/inward/record.url?scp=84883401986&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84883401986&partnerID=8YFLogxK

U2 - 10.1017/S0007114513000019

DO - 10.1017/S0007114513000019

M3 - Article

C2 - 23388502

AN - SCOPUS:84883401986

VL - 110

SP - 1068

EP - 1074

JO - British Journal of Nutrition

JF - British Journal of Nutrition

SN - 0007-1145

IS - 6

ER -