Gastrin cell populations after highly selective vagotomy in the dog

Daniel H. Dunn, Cezar Decanini, Margaret E. Bonsack, M. Michael Eisenberg, John P Delaney

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Highly selective vagotomy was performed on five dogs. Postoperatively, gastrin cell (G cell) hyperplasia occurred in all dogs. Mean preoperative G cell numbers increased from 350 to 530/cm mucosal length (p < 0.02). Antral tissue gastrin also increased by 100 per cent (6.7 × 106 to 13.7 × 106 pg/gm tissue, p < 0.05). Basal and stimulated serum gastrin were unchanged following highly selective vagotomy. The cause for G cell hyperplasia is not clear, but is probably multifactorial.

Original languageEnglish (US)
Pages (from-to)111-115
Number of pages5
JournalThe American Journal of Surgery
Volume137
Issue number1
DOIs
StatePublished - Jan 1 1979

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Proximal Gastric Vagotomy
Gastrin-Secreting Cells
Gastrins
Dogs
Hyperplasia
Population
Cell Count
Serum

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Dunn, D. H., Decanini, C., Bonsack, M. E., Eisenberg, M. M., & Delaney, J. P. (1979). Gastrin cell populations after highly selective vagotomy in the dog. The American Journal of Surgery, 137(1), 111-115. https://doi.org/10.1016/0002-9610(79)90020-5

Gastrin cell populations after highly selective vagotomy in the dog. / Dunn, Daniel H.; Decanini, Cezar; Bonsack, Margaret E.; Eisenberg, M. Michael; Delaney, John P.

In: The American Journal of Surgery, Vol. 137, No. 1, 01.01.1979, p. 111-115.

Research output: Contribution to journalArticle

Dunn, DH, Decanini, C, Bonsack, ME, Eisenberg, MM & Delaney, JP 1979, 'Gastrin cell populations after highly selective vagotomy in the dog', The American Journal of Surgery, vol. 137, no. 1, pp. 111-115. https://doi.org/10.1016/0002-9610(79)90020-5
Dunn, Daniel H. ; Decanini, Cezar ; Bonsack, Margaret E. ; Eisenberg, M. Michael ; Delaney, John P. / Gastrin cell populations after highly selective vagotomy in the dog. In: The American Journal of Surgery. 1979 ; Vol. 137, No. 1. pp. 111-115.
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