Abstract
A recently introduced method called SWIFT (SWeep Imaging with Fourier Transform) is a fundamentally different approach to MRI which is particularly well suited to imaging objects with extremely fast spin-spin relaxation rates. The method exploits a frequency-swept excitation pulse and virtually simultaneous signal acquisition in a time-shared mode. Correlation of the spin system response with the excitation pulse function is used to extract the signals of interest. With SWIFT, image quality is highly dependent on producing uniform and broadband spin excitation. These requirements are satisfied by using frequency-modulated pulses belonging to the hyperbolic secant family (HSn pulses). This article describes the experimental steps needed to properly implement HSn pulses in SWIFT. In addition, properties of HSn pulses in the rapid passage, linear region are investigated, followed by an analysis of the pulses after inserting the "gaps" needed for time-shared excitation and acquisition. Finally, compact expressions are presented to estimate the amplitude and flip angle of the HSn pulses, as well as the relative energy deposited by the SWIFT sequence.
Original language | English (US) |
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Pages (from-to) | 267-273 |
Number of pages | 7 |
Journal | Journal of Magnetic Resonance |
Volume | 193 |
Issue number | 2 |
DOIs | |
State | Published - Aug 2008 |
Bibliographical note
Funding Information:This work was supported by NIH Grants R01 CA92004, P41 RR008079, P30 NS057091, the Keck Foundation, the MIND Institute, and the Minnesota Medical Foundation (4T TEM coil) Grant # 3761-9236-07.
Keywords
- Adiabatic pulse
- Correlation spectroscopy
- Frequency-modulated pulse
- MRI
- Radial imaging