Historically experimentation has been a cornerstone to the advancement of our knowledge of the behavior of reinforced concrete structural systems. Simulation integrated with experimentation has provided researchers with the ability to extend those experimental results to a braad range of applications. This paper will present an overview of some of the key advancements that have been made through this integrated approach to research. A perspective will be provided regarding the potential impact of programs such as the George E. Brown, Jr., Network tor Earthquake Engineering Simulation (NEES) on the transformation of future research. This program represents an $82 Million investment in networked research equipment infrastructure that will be available as an international resource.