Fungemia por espécies de Candida em hospital pediátrico da cidade de São Paulo, Brasil: Estudo no período de 2007 a 2010

Translated title of the contribution: Fungemia caused by Candida species in a children's public hospital in the city of São Paulo, Brazil: Study in the period 2007-2010

Vanessa Kummer Perinazzo Oliveira, Luciana da Silva Ruiz, Nélio Alessandro Jesus Oliveira, Débora Moreira, Rosane Christine Hahn, Analy Salles de Azevedo Melo, Angela Satie Nishikaku, Claudete Rodrigues Paula

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Candidemia remains a major cause of morbidity and mortality in the health care environment. The epidemiology of Candida infection is changing, mainly in relation to the number of episodes caused by species C. non-albicans. The overall objective of this study was to evaluate the frequency of yeasts of the genus Candida, in a four-year period, isolated from blood of pediatric patients hospitalized in a public hospital of the city of São Paulo, Brazil. In this period, yeasts from blood of 104 patients were isolated and, the identified species of Candida by phenotypic and genotypic methods were: C. albicans (39/104), C. tropicalis (25/104), C. parapsilosis (23/104), Pichia anomala (6/104), C. guilliermondii (5/104), C. krusei (3/104), C. glabrata (2/104) and C. pararugosa (1/104). During the period of the study, a higher frequency of isolates of C. non-albicans (63.55%) (p = 0.0286) was verified. In this study we verified the increase of the non-albicans species throughout the years (mainly in 2009 and 2010). Thus, considering the peculiarities presented by Candida species, a correct identification of species is recommended to lead to a faster diagnosis and an efficient treatment.

Translated title of the contributionFungemia caused by Candida species in a children's public hospital in the city of São Paulo, Brazil: Study in the period 2007-2010
Original languagePortuguese
Pages (from-to)301-305
Number of pages5
JournalRevista do Instituto de Medicina Tropical de Sao Paulo
Volume56
Issue number4
DOIs
StatePublished - 2014

Keywords

  • Candida
  • Candidemia
  • Pediatric

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