Functionalizing calcium phosphate biomaterials with antibacterial silver particles

Jae Sung Lee, William L. Murphy

Research output: Contribution to journalArticlepeer-review

127 Scopus citations

Abstract

Antimicrobial silver particles are created on calcium phosphate (CaP) biomaterials by sequentially incubating in citric acid and silver nitrate solutions. The subsequent silver release kinetics and released dosage are controlled by simply changing the solution conditions during growth of silver particles. Released silver efficiently suppresses the growth of gram-positive Staphylococcus aureus and gram-negative Escherichia coli without significant cytotoxicity to eukaryotic cells.

Original languageEnglish (US)
Pages (from-to)1173-1179
Number of pages7
JournalAdvanced Materials
Volume25
Issue number8
DOIs
StatePublished - Feb 25 2013
Externally publishedYes

Keywords

  • drug delivery
  • functional coatings
  • medical application
  • silver
  • tissue engineering

Fingerprint

Dive into the research topics of 'Functionalizing calcium phosphate biomaterials with antibacterial silver particles'. Together they form a unique fingerprint.

Cite this