A new pentadentate ligand, N,N-bis(2-pyridylmethyl)-N-bis(2-pyridyl)methylamine (N4Py), has been prepared. The corresponding iron(II) complex, [N4PyFe(CH3CN)](ClO4)2, serves as a functional model for the active site of ironbleomycin. Upon treatment with H2O2 the formation of a purple intermediate has been observed, which has been characterized as an iron(III)-hydroperoxide complex. This N4Py-iron-hydroperoxide system has proven to be an active oxidation catalyst.
Bibliographical noteFunding Information:
Financial support of Unilever Research, Vlaardingen and the National Institutes of Health (GM-33162) is gratefully acknowledged.
- Hydroperoxide compounds
- Nonheme iron compounds
- Oxygen activation