Functional magnetic resonance imaging of motor cortex: Hemispheric asymmetry and handedness

Seong Gi Kim, James Ashe, Kristy Hendrich, Jutta M Ellermann, Hellmut Merkle, Kamil Ugurbil, Apostolos P Georgopoulos

Research output: Contribution to journalArticlepeer-review

884 Scopus citations

Abstract

A hemispheric asymmetry in the functional activation of the human motor cortex during contralateral (C) and ipsilateral (I) finger movements, especially in right-handed subjects, was documented with nuclear magnetic resonance imaging at high field strength (4 tesla). Whereas the right motor cortex was activated mostly during contralateral finger movements in both right-handed (C/I mean area of activation = 36.8) and left-handed (C/I = 29.9) subjects, the left motor cortex was activated substantially during ipsilateral movements in left-handed subjects (C/I = 5.4) and even more so in right-handed subjects (C/I = 1.3).

Original languageEnglish (US)
Pages (from-to)615-617
Number of pages3
JournalScience
Volume261
Issue number5121
DOIs
StatePublished - 1993

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