Functional impairment in COPD patients: The impact of anxiety and depression

H. Florence Seung Kim, Mark E. Kunik, Victor A. Molinari, Stephany L. Hillman, Suleman Lalani, Claudia A. Orengo, Nancy J. Petersen, Ziad Nahas, Sheila Goodnight-White

Research output: Contribution to journalArticlepeer-review

257 Scopus citations


The authors examined the relationship between functional status and comorbid anxiety and depression and the relationship between utilization of health care resources and psychopathology in elderly patients with chronic obstructive pulmonary disease (COPD). Elderly male veterans (N = 43) with COPD completed anxiety, depression, and functional status measures. The authors constructed regression models to explore the contribution of COPD severity, medical burden, depression, and anxiety to the dependent variables of functional impairment and health care utilization. Anxiety and depression contributed significantly to the overall variance in functional status of COPD patients, over and above medical burden and COPD severity, as measured by the 8 scales of the Medical Outcomes Study (MOS) 36-item Short Form Health Survey. Surprisingly, medical burden and COPD severity did not contribute significantly to overall variance in functional status. Few patients were receiving any treatment for anxiety or depression.

Original languageEnglish (US)
Pages (from-to)465-471
Number of pages7
Issue number6
StatePublished - 2000

Bibliographical note

Funding Information:
This research was funded by a grant from the VA Rehabilitation , Research and Development Center for Excellence on Healthy Aging with Disabilities .

Copyright 2018 Elsevier B.V., All rights reserved.


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