Feasibility of continuously and simultaneously recording visual evoked potentials (VEPs) with fMRI was assessed by quantitatively comparing cortical source images by means of receiver operating characteristic (ROC) curve analysis. The averaged EEG source images coincided well with simultaneously acquired fMRI activations. Strong correlation was found between the cortical source images of VEPs recorded inside and outside the scanner. Application of fMRI prior information strengthened correlation between estimated source images as well as resulted in source estimates with higher spatial resolution. The present results demonstrate that reliable cortical source images can be acquired during simultaneous fMRI scanning and they may be used for multimodal functional source imaging studies.
Bibliographical noteFunding Information:
This work was supported in part by NSF BES-0411898, NIH RO1 EB00178, NIH RO1 EB00329, Biomedical Engineering Institute of the University of Minnesota, BTRR P41 008079, KECK Foundation and MIND Institute. CH Im was supported in part by the Korea Research Foundation Grant funded by Korea Government (MOEHRD, Basic Research Promotion Fund) (M01-2005-000-10132-0).
- Cortical source imaging
- Human brain mapping
- Multimodal integration
- Simultaneous fMRI and EEG