TY - JOUR
T1 - Fruit intake decreases risk of incident type 2 diabetes
T2 - an updated meta-analysis
AU - Li, Shuangshuang
AU - Miao, Song
AU - Huang, Yubei
AU - Liu, Zhaolu
AU - Tian, Huan
AU - Yin, Xiuxiu
AU - Tang, Weihong
AU - Steffen, Lyn M.
AU - Xi, Bo
N1 - Publisher Copyright:
© 2014, Springer Science+Business Media New York.
PY - 2015/3
Y1 - 2015/3
N2 - Association between fruit intake and risk of type 2 diabetes is inconsistent. In this study, we performed a meta-analysis of all prospective cohort studies to clarify the association between fruit intake and risk of type 2 diabetes. Relevant studies were identified by searches of the PubMed and Embase databases up to November 2013. The summary relative risks of association were obtained using a fixed- or random-effects model. A total of nine prospective studies (403,259 participants, including 27,940 with incident type 2 diabetes) from seven publications were included in the meta-analysis of fruit intake and risk of type 2 diabetes. We found that individuals in the highest category of fruit intake had a reduced risk of type 2 diabetes (relative risk 0.92, 95 % confidence interval 0.86–0.97, p = 0.003) compared to those in the lowest category, with moderate evidence of between-study heterogeneity (I2 = 37.6 %, p = 0.12). There was an evident non-linear association of fruit intake with type 2 diabetes (P for nonlinearity <0.001). A non-linear threshold of 200 g/day of fruit intake was identified and the risk of type 2 diabetes reduced by about 13 % at this cut-off. Our findings are consistent with diet recommendations to consume about 200 g/day of fruits to prevent type 2 diabetes.
AB - Association between fruit intake and risk of type 2 diabetes is inconsistent. In this study, we performed a meta-analysis of all prospective cohort studies to clarify the association between fruit intake and risk of type 2 diabetes. Relevant studies were identified by searches of the PubMed and Embase databases up to November 2013. The summary relative risks of association were obtained using a fixed- or random-effects model. A total of nine prospective studies (403,259 participants, including 27,940 with incident type 2 diabetes) from seven publications were included in the meta-analysis of fruit intake and risk of type 2 diabetes. We found that individuals in the highest category of fruit intake had a reduced risk of type 2 diabetes (relative risk 0.92, 95 % confidence interval 0.86–0.97, p = 0.003) compared to those in the lowest category, with moderate evidence of between-study heterogeneity (I2 = 37.6 %, p = 0.12). There was an evident non-linear association of fruit intake with type 2 diabetes (P for nonlinearity <0.001). A non-linear threshold of 200 g/day of fruit intake was identified and the risk of type 2 diabetes reduced by about 13 % at this cut-off. Our findings are consistent with diet recommendations to consume about 200 g/day of fruits to prevent type 2 diabetes.
KW - Fruit
KW - Meta-analysis
KW - Type 2 diabetes
UR - https://www.scopus.com/pages/publications/84939883901
UR - https://www.scopus.com/inward/citedby.url?scp=84939883901&partnerID=8YFLogxK
U2 - 10.1007/s12020-014-0351-6
DO - 10.1007/s12020-014-0351-6
M3 - Article
C2 - 25074631
AN - SCOPUS:84939883901
SN - 1355-008X
VL - 48
SP - 454
EP - 460
JO - Endocrine
JF - Endocrine
IS - 2
ER -
